| Reaction Details |
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 | Report a problem with these data |
| Target | D(3) dopamine receptor |
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| Ligand | BDBM50589749 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_2194223 (CHEMBL5106583) |
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| Ki | 81±n/a nM |
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| Citation |  Pavleti?, P; Semeano, A; Yano, H; Bonifazi, A; Giorgioni, G; Piergentili, A; Quaglia, W; Sabbieti, MG; Agas, D; Santoni, G; Pallini, R; Ricci-Vitiani, L; Sabato, E; Vistoli, G; Del Bello, F Highly Potent and Selective Dopamine D J Med Chem65:12124-12139 (2022) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| D(3) dopamine receptor |
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| Name: | D(3) dopamine receptor |
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| Synonyms: | DRD3 | DRD3_HUMAN | Dopamine D3 receptor |
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| Type: | PROTEIN |
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| Mol. Mass.: | 44213.40 |
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| Organism: | Homo sapiens |
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| Description: | ChEMBL_105671 |
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| Residue: | 400 |
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| Sequence: | MASLSQLSGHLNYTCGAENSTGASQARPHAYYALSYCALILAIVFGNGLVCMAVLKERAL
QTTTNYLVVSLAVADLLVATLVMPWVVYLEVTGGVWNFSRICCDVFVTLDVMMCTASILN
LCAISIDRYTAVVMPVHYQHGTGQSSCRRVALMITAVWVLAFAVSCPLLFGFNTTGDPTV
CSISNPDFVIYSSVVSFYLPFGVTVLVYARIYVVLKQRRRKRILTRQNSQCNSVRPGFPQ
QTLSPDPAHLELKRYYSICQDTALGGPGFQERGGELKREEKTRNSLSPTIAPKLSLEVRK
LSNGRLSTSLKLGPLQPRGVPLREKKATQMVAIVLGAFIVCWLPFFLTHVLNTHCQTCHV
SPELYSATTWLGYVNSALNPVIYTTFNIEFRKAFLKILSC
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| BDBM50589749 |
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| n/a |
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| Name | BDBM50589749 |
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| Synonyms: | CHEMBL5199358 |
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| Type | Small organic molecule |
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| Emp. Form. | C25H31N3O5 |
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| Mol. Mass. | 453.5307 |
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| SMILES | OC(=O)C(O)=O.O=C1CCc2ccccc2N1CCCCN1CCN(CC1)c1ccccc1 |
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| Structure | 
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