| Reaction Details |
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 | Report a problem with these data |
| Target | D(4) dopamine receptor |
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| Ligand | BDBM50589757 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_2194224 (CHEMBL5106584) |
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| Ki | 0.602560±n/a nM |
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| Citation |  Pavleti?, P; Semeano, A; Yano, H; Bonifazi, A; Giorgioni, G; Piergentili, A; Quaglia, W; Sabbieti, MG; Agas, D; Santoni, G; Pallini, R; Ricci-Vitiani, L; Sabato, E; Vistoli, G; Del Bello, F Highly Potent and Selective Dopamine D J Med Chem65:12124-12139 (2022) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| D(4) dopamine receptor |
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| Name: | D(4) dopamine receptor |
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| Synonyms: | D(2C) dopamine receptor | DOPAMINE D4 | DOPAMINE D4.2 | DOPAMINE D4.4 | DRD4 | DRD4_HUMAN | Dopamine D4 receptor |
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| Type: | Enzyme |
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| Mol. Mass.: | 48373.19 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P21917 |
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| Residue: | 419 |
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| Sequence: | MGNRSTADADGLLAGRGPAAGASAGASAGLAGQGAAALVGGVLLIGAVLAGNSLVCVSVA
TERALQTPTNSFIVSLAAADLLLALLVLPLFVYSEVQGGAWLLSPRLCDALMAMDVMLCT
ASIFNLCAISVDRFVAVAVPLRYNRQGGSRRQLLLIGATWLLSAAVAAPVLCGLNDVRGR
DPAVCRLEDRDYVVYSSVCSFFLPCPLMLLLYWATFRGLQRWEVARRAKLHGRAPRRPSG
PGPPSPTPPAPRLPQDPCGPDCAPPAPGLPRGPCGPDCAPAAPSLPQDPCGPDCAPPAPG
LPPDPCGSNCAPPDAVRAAALPPQTPPQTRRRRRAKITGRERKAMRVLPVVVGAFLLCWT
PFFVVHITQALCPACSVPPRLVSAVTWLGYVNSALNPVIYTVFNAEFRNVFRKALRACC
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| BDBM50589757 |
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| n/a |
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| Name | BDBM50589757 |
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| Synonyms: | CHEMBL5172201 |
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| Type | Small organic molecule |
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| Emp. Form. | C24H28ClN3O5 |
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| Mol. Mass. | 473.949 |
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| SMILES | OC(=O)C(O)=O.Clc1ccccc1N1CCN(CCCN2C(=O)CCc3ccccc23)CC1 |
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| Structure | 
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