| Reaction Details |
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 | Report a problem with these data |
| Target | Serine/threonine-protein kinase PAK 5 |
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| Ligand | BDBM50429615 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_2198937 (CHEMBL5111453) |
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| IC50 | 96±n/a nM |
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| Citation |  Drewry, DH; Potjewyd, FM; Bayati, A; Smith, JL; Dickmander, RJ; Howell, S; Taft-Benz, S; Min, SM; Hossain, MA; Heise, M; McPherson, PS; Moorman, NJ; Axtman, AD Identification and Utilization of a Chemical Probe to Interrogate the Roles of PIKfyve in the Lifecycle of ?-Coronaviruses. J Med Chem65:12860-12882 (2022) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Serine/threonine-protein kinase PAK 5 |
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| Name: | Serine/threonine-protein kinase PAK 5 |
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| Synonyms: | KIAA1264 | PAK5 | PAK5_HUMAN | PAK7 | PAK7/PAK5 | Protein Kinase PAK5 | Serine/threonine-protein kinase (PAK7) | Serine/threonine-protein kinase PAK 5 | Serine/threonine-protein kinase PAK7 |
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| Type: | Protein |
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| Mol. Mass.: | 80760.58 |
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| Organism: | Homo sapiens (Human) |
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| Description: | Q9P286 |
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| Residue: | 719 |
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| Sequence: | MFGKKKKKIEISGPSNFEHRVHTGFDPQEQKFTGLPQQWHSLLADTANRPKPMVDPSCIT
PIQLAPMKTIVRGNKPCKETSINGLLEDFDNISVTRSNSLRKESPPTPDQGASSHGPGHA
EENGFITFSQYSSESDTTADYTTEKYREKSLYGDDLDPYYRGSHAAKQNGHVMKMKHGEA
YYSEVKPLKSDFARFSADYHSHLDSLSKPSEYSDLKWEYQRASSSSPLDYSFQFTPSRTA
GTSGCSKESLAYSESEWGPSLDDYDRRPKSSYLNQTSPQPTMRQRSRSGSGLQEPMMPFG
ASAFKTHPQGHSYNSYTYPRLSEPTMCIPKVDYDRAQMVLSPPLSGSDTYPRGPAKLPQS
QSKSGYSSSSHQYPSGYHKATLYHHPSLQSSSQYISTASYLSSLSLSSSTYPPPSWGSSS
DQQPSRVSHEQFRAALQLVVSPGDPREYLANFIKIGEGSTGIVCIATEKHTGKQVAVKKM
DLRKQQRRELLFNEVVIMRDYHHDNVVDMYSSYLVGDELWVVMEFLEGGALTDIVTHTRM
NEEQIATVCLSVLRALSYLHNQGVIHRDIKSDSILLTSDGRIKLSDFGFCAQVSKEVPKR
KSLVGTPYWMAPEVISRLPYGTEVDIWSLGIMVIEMIDGEPPYFNEPPLQAMRRIRDSLP
PRVKDLHKVSSVLRGFLDLMLVREPSQRATAQELLGHPFLKLAGPPSCIVPLMRQYRHH
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| BDBM50429615 |
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| n/a |
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| Name | BDBM50429615 |
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| Synonyms: | CHEMBL2334586 |
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| Type | Small organic molecule |
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| Emp. Form. | C20H20N4O |
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| Mol. Mass. | 332.399 |
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| SMILES | CC(C)(O)C#Cc1ccc2[nH]c3CCCc4cnc(N)nc4-c3c2c1 |
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| Structure | 
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