| Reaction Details |
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 | Report a problem with these data |
| Target | Testis-specific serine/threonine-protein kinase 1 |
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| Ligand | BDBM50429615 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_2198939 (CHEMBL5111455) |
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| IC50 | 210±n/a nM |
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| Citation |  Drewry, DH; Potjewyd, FM; Bayati, A; Smith, JL; Dickmander, RJ; Howell, S; Taft-Benz, S; Min, SM; Hossain, MA; Heise, M; McPherson, PS; Moorman, NJ; Axtman, AD Identification and Utilization of a Chemical Probe to Interrogate the Roles of PIKfyve in the Lifecycle of ?-Coronaviruses. J Med Chem65:12860-12882 (2022) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Testis-specific serine/threonine-protein kinase 1 |
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| Name: | Testis-specific serine/threonine-protein kinase 1 |
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| Synonyms: | SPOGA1 | SPOGA4 | STK22A | STK22D | TSSK1 | TSSK1B | TSSK1_HUMAN | Testis-specific serine/threonine-protein kinase 1 |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 41624.03 |
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| Organism: | Homo sapiens (Human) |
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| Description: | gi_14042947 |
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| Residue: | 367 |
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| Sequence: | MDDAAVLKRRGYLLGINLGEGSYAKVKSAYSERLKFNVAIKIIDRKKAPADFLEKFLPRE
IEILAMLNHCSIIKTYEIFETSHGKVYIVMELAVQGDLLELIKTRGALHEDEARKKFHQL
SLAIKYCHDLDVVHRDLKCDNLLLDKDFNIKLSDFSFSKRCLRDDSGRMALSKTFCGSPA
YAAPEVLQGIPYQPKVYDIWSLGVILYIMVCGSMPYDDSNIKKMLRIQKEHRVNFPRSKH
LTGECKDLIYHMLQPDVNRRLHIDEILSHCWMQPKARGSPSVAINKEGESSRGTEPLWTP
EPGSDKKSATKLEPEGEAQPQAQPETKPEGTAMQMSRQSEILGFPSKPSTMETEEGPPQQ
PPETRAQ
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| BDBM50429615 |
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| n/a |
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| Name | BDBM50429615 |
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| Synonyms: | CHEMBL2334586 |
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| Type | Small organic molecule |
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| Emp. Form. | C20H20N4O |
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| Mol. Mass. | 332.399 |
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| SMILES | CC(C)(O)C#Cc1ccc2[nH]c3CCCc4cnc(N)nc4-c3c2c1 |
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| Structure | 
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