| Reaction Details |
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 | Report a problem with these data |
| Target | Glutamate receptor ionotropic, kainate 5 |
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| Ligand | BDBM50591735 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_2201506 (CHEMBL5114214) |
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| Ki | 100000±n/a nM |
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| Citation |  Jiang, X; Wu, K; Bai, R; Zhang, P; Zhang, Y Functionalized quinoxalinones as privileged structures with broad-ranging pharmacological activities. Eur J Med Chem229:0 (2022) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Glutamate receptor ionotropic, kainate 5 |
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| Name: | Glutamate receptor ionotropic, kainate 5 |
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| Synonyms: | GRIK2 | GRIK5 | GRIK5_HUMAN | Glutamate receptor ionotropic kainate 5 | Glutamate receptor, ionotropic kainate 5 | Glutamate-Kainate 5 | Ionotropic glutamate receptor kainate 2/5 |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 109280.81 |
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| Organism: | Homo sapiens (Human) |
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| Description: | Glutamate-Kainate 5 Grik5 HUMAN::Q16478 |
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| Residue: | 980 |
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| Sequence: | MPAELLLLLIVAFASPSCQVLSSLRMAAILDDQTVCGRGERLALALAREQINGIIEVPAK
ARVEVDIFELQRDSQYETTDTMCQILPKGVVSVLGPSSSPASASTVSHICGEKEIPHIKV
GPEETPRLQYLRFASVSLYPSNEDVSLAVSRILKSFNYPSASLICAKAECLLRLEELVRG
FLISKETLSVRMLDDSRDPTPLLKEIRDDKVSTIIIDANASISHLILRKASELGMTSAFY
KYILTTMDFPILHLDGIVEDSSNILGFSMFNTSHPFYPEFVRSLNMSWRENCEASTYLGP
ALSAALMFDAVHVVVSAVRELNRSQEIGVKPLACTSANIWPHGTSLMNYLRMVEYDGLTG
RVEFNSKGQRTNYTLRILEKSRQGHREIGVWYSNRTLAMNATTLDINLSQTLANKTLVVT
TILENPYVMRRPNFQALSGNERFEGFCVDMLRELAELLRFRYRLRLVEDGLYGAPEPNGS
WTGMVGELINRKADLAVAAFTITAEREKVIDFSKPFMTLGISILYRVHMGRKPGYFSFLD
PFSPAVWLFMLLAYLAVSCVLFLAARLSPYEWYNPHPCLRARPHILENQYTLGNSLWFPV
GGFMQQGSEIMPRALSTRCVSGVWWAFTLIIISSYTANLAAFLTVQRMEVPVESADDLAD
QTNIEYGTIHAGSTMTFFQNSRYQTYQRMWNYMQSKQPSVFVKSTEEGIARVLNSRYAFL
LESTMNEYHRRLNCNLTQIGGLLDTKGYGIGMPLGSPFRDEITLAILQLQENNRLEILKR
KWWEGGRCPKEEDHRAKGLGMENIGGIFIVLICGLIIAVFVAVMEFIWSTRRSAESEEVS
VCQEMLQELRHAVSCRKTSRSRRRRRPGGPSRALLSLRAVREMRLSNGKLYSAGAGGDAG
SAHGGPQRLLDDPGPPSGARPAAPTPCTHVRVCQECRRIQALRASGAGAPPRGLGVPAEA
TSPPRPRPGPAGPRELAEHE
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| BDBM50591735 |
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| n/a |
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| Name | BDBM50591735 |
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| Synonyms: | CHEMBL5209119 |
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| Type | Small organic molecule |
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| Emp. Form. | C18H13N3O4 |
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| Mol. Mass. | 335.3135 |
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| SMILES | OCC#Cc1ccc2n(NC(=O)c3ccccc3)c(=O)c(=O)[nH]c2c1 |
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| Structure | 
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