| Reaction Details |
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 | Report a problem with these data |
| Target | Cytochrome P450 4B1 |
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| Ligand | BDBM50591915 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_2202731 (CHEMBL5115439) |
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| IC50 | 1100±n/a nM |
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| Citation |  Kampschulte, N; Berking, T; Çelik, IE; Kirsch, SF; Schebb, NH Inhibition of cytochrome P450 monooxygenase-catalyzed oxylipin formation by flavonoids: Evaluation of structure-activity relationship towards CYP4F2-selective inhibitors. Eur J Med Chem238:0 (2022) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Cytochrome P450 4B1 |
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| Name: | Cytochrome P450 4B1 |
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| Synonyms: | 1.14.14.1 | CP4B1_HUMAN | CYP4B1 | CYPIVB1 | Cytochrome P450 4B1 | Cytochrome P450-HP |
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| Type: | PROTEIN |
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| Mol. Mass.: | 59005.59 |
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| Organism: | Homo sapiens |
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| Description: | ChEMBL_119703 |
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| Residue: | 511 |
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| Sequence: | MVPSFLSLSFSSLGLWASGLILVLGFLKLIHLLLRRQTLAKAMDKFPGPPTHWLFGHALE
IQETGSLDKVVSWAHQFPYAHPLWFGQFIGFLNIYEPDYAKAVYSRGDPKAPDVYDFFLQ
WIGRGLLVLEGPKWLQHRKLLTPGFHYDVLKPYVAVFTESTRIMLDKWEEKAREGKSFDI
FCDVGHMALNTLMKCTFGRGDTGLGHRDSSYYLAVSDLTLLMQQRLVSFQYHNDFIYWLT
PHGRRFLRACQVAHDHTDQVIRERKAALQDEKVRKKIQNRRHLDFLDILLGARDEDDIKL
SDADLRAEVDTFMFEGHDTTTSGISWFLYCMALYPEHQHRCREEVREILGDQDFFQWDDL
GKMTYLTMCIKESFRLYPPVPQVYRQLSKPVTFVDGRSLPAGSLISMHIYALHRNSAVWP
DPEVFDSLRFSTENASKRHPFAFMPFSAGPRNCIGQQFAMSEMKVVTAMCLLRFEFSLDP
SRLPIKMPQLVLRSKNGFHLHLKPLGPGSGK
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| BDBM50591915 |
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| n/a |
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| Name | BDBM50591915 |
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| Synonyms: | CHEMBL2130955 |
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| Type | Small organic molecule |
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| Emp. Form. | C16H9F3O2 |
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| Mol. Mass. | 290.2367 |
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| SMILES | FC(F)(F)c1ccc(cc1)-c1cc(=O)c2ccccc2o1 |
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| Structure | 
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