| Reaction Details |
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 | Report a problem with these data |
| Target | Sigma non-opioid intracellular receptor 1 |
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| Ligand | BDBM50592426 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_2204130 (CHEMBL5116838) |
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| Ki | 2.0±n/a nM |
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| Citation |  Levoin, N; Murthy, AVR; Narendar, V; Kumar, NS; Aparna, P; Bhavani, AKD; Reddy, CR; Mosset, P; Grée, R Discovery of potent dual ligands for dopamine D4 and ?1 receptors. Bioorg Med Chem69:0 (2022) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Sigma non-opioid intracellular receptor 1 |
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| Name: | Sigma non-opioid intracellular receptor 1 |
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| Synonyms: | Aging-associated gene 8 protein | OPRS1 | SGMR1_HUMAN | SIG-1R | SIGMAR1 | SR-BP | SR31747-binding protein | SRBP | Sigma 1-type opioid receptor | Sigma opioid receptor | Sigma1R | hSigmaR1 |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 25124.85 |
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| Organism: | Homo sapiens (Human) |
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| Description: | Q99720 |
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| Residue: | 223 |
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| Sequence: | MQWAVGRRWAWAALLLAVAAVLTQVVWLWLGTQSFVFQREEIAQLARQYAGLDHELAFSR
LIVELRRLHPGHVLPDEELQWVFVNAGGWMGAMCLLHASLSEYVLLFGTALGSRGHSGRY
WAEISDTIISGTFHQWREGTTKSEVFYPGETVVHGPGEATAVEWGPNTWMVEYGRGVIPS
TLAFALADTVFSTQDFLTLFYTLRSYARGLRLELTTYLFGQDP
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| BDBM50592426 |
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| n/a |
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| Name | BDBM50592426 |
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| Synonyms: | CHEMBL4547253 |
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| Type | Small organic molecule |
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| Emp. Form. | C21H22BrFN4 |
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| Mol. Mass. | 429.329 |
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| SMILES | Fc1ccc(CN2CCC(CC2)n2cc(Cc3ccc(Br)cc3)nn2)cc1 |
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| Structure | 
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