| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Choline kinase alpha |
|---|
| Ligand | BDBM50166190 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_305138 (CHEMBL832433) |
|---|
| IC50 | 20600±n/a nM |
|---|
| Citation |  Sánchez-Martín, R; Campos, JM; Conejo-García, A; Cruz-López, O; Báñez-Coronel, M; Rodríguez-González, A; Gallo, MA; Lacal, JC; Espinosa, A Symmetrical bis-quinolinium compounds: new human choline kinase inhibitors with antiproliferative activity against the HT-29 cell line. J Med Chem48:3354-63 (2005) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Choline kinase alpha |
|---|
| Name: | Choline kinase alpha |
|---|
| Synonyms: | CHK | CHKA | CHKA_HUMAN | CKI | Choline kinase alpha |
|---|
| Type: | PROTEIN |
|---|
| Mol. Mass.: | 52248.44 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | ChEMBL_1290064 |
|---|
| Residue: | 457 |
|---|
| Sequence: | MKTKFCTGGEAEPSPLGLLLSCGSGSAAPAPGVGQQRDAASDLESKQLGGQQPPLALPPP
PPLPLPLPLPQPPPPQPPADEQPEPRTRRRAYLWCKEFLPGAWRGLREDEFHISVIRGGL
SNMLFQCSLPDTTATLGDEPRKVLLRLYGAILQMRSCNKEGSEQAQKENEFQGAEAMVLE
SVMFAILAERSLGPKLYGIFPQGRLEQFIPSRRLDTEELSLPDISAEIAEKMATFHGMKM
PFNKEPKWLFGTMEKYLKEVLRIKFTEESRIKKLHKLLSYNLPLELENLRSLLESTPSPV
VFCHNDCQEGNILLLEGRENSEKQKLMLIDFEYSSYNYRGFDIGNHFCEWMYDYSYEKYP
FFRANIRKYPTKKQQLHFISSYLPAFQNDFENLSTEEKSIIKEEMLLEVNRFALASHFLW
GLWSIVQAKISSIEFGYMDYAQARFDAYFHQKRKLGV
|
|
|
|---|
| BDBM50166190 |
|---|
| n/a |
|---|
| Name | BDBM50166190 |
|---|
| Synonyms: | Bisquinolinium derivative | CHEMBL191818 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C32H26Cl2N4 |
|---|
| Mol. Mass. | 537.481 |
|---|
| SMILES | Clc1ccc2c(c1)n(Cc1cccc(c1)-c1cccc(Cn3ccc(=[NH2+])c4ccc(Cl)cc34)c1)ccc2=[NH2+] |
|---|
| Structure | 
|
|---|
Search and Browse
