| Reaction Details |
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 | Report a problem with these data |
| Target | Adenosine kinase |
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| Ligand | BDBM50166236 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_304730 (CHEMBL876476) |
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| IC50 | 3600±n/a nM |
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| Citation |  Bookser, BC; Matelich, MC; Ollis, K; Ugarkar, BG Adenosine kinase inhibitors. 4. 6,8-Disubstituted purine nucleoside derivatives. Synthesis, conformation, and enzyme inhibition. J Med Chem48:3389-99 (2005) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Adenosine kinase |
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| Name: | Adenosine kinase |
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| Synonyms: | ADK | ADK_HUMAN |
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| Type: | PROTEIN |
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| Mol. Mass.: | 40545.97 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_1467841 |
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| Residue: | 362 |
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| Sequence: | MAAAEEEPKPKKLKVEAPQALRENILFGMGNPLLDISAVVDKDFLDKYSLKPNDQILAED
KHKELFDELVKKFKVEYHAGGSTQNSIKVAQWMIQQPHKAATFFGCIGIDKFGEILKRKA
AEAHVDAHYYEQNEQPTGTCAACITGDNRSLIANLAAANCYKKEKHLDLEKNWMLVEKAR
VCYIAGFFLTVSPESVLKVAHHASENNRIFTLNLSAPFISQFYKESLMKVMPYVDILFGN
ETEAATFAREQGFETKDIKEIAKKTQALPKMNSKRQRIVIFTQGRDDTIMATESEVTAFA
VLDQDQKEIIDTNGAGDAFVGGFLSQLVSDKPLTECIRAGHYAASIIIRRTGCTFPEKPD
FH
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| BDBM50166236 |
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| n/a |
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| Name | BDBM50166236 |
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| Synonyms: | (2R,3R,4S,5R)-2-(8-Chloro-6-phenylamino-purin-9-yl)-5-hydroxymethyl-tetrahydro-furan-3,4-diol | CHEMBL192259 |
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| Type | Small organic molecule |
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| Emp. Form. | C16H16ClN5O4 |
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| Mol. Mass. | 377.782 |
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| SMILES | OC[C@H]1O[C@H]([C@H](O)[C@@H]1O)n1c(Cl)nc2c(Nc3ccccc3)ncnc12 |
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| Structure | 
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