| Reaction Details |
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 | Report a problem with these data |
| Target | C-X-C chemokine receptor type 3 |
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| Ligand | BDBM50595462 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_2216804 (CHEMBL5129936) |
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| IC50 | 3.0±n/a nM |
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| Citation |  Meyer, EA; Äänismaa, P; Froidevaux, S; Keller, M; Piali, L; Caroff, E Discovery and J Med Chem65:11513-11532 (2022) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| C-X-C chemokine receptor type 3 |
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| Name: | C-X-C chemokine receptor type 3 |
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| Synonyms: | AAO92295.1 | C-X-C chemokine receptor type 3 | C-X-C chemokine receptor type 3 (CXCR3) | C-X-C chemokine receptor type 3 (CXCR3A) | CXCR3 | CXCR3A | CXCR3_HUMAN | GPR9 | chemokine (C-X-C motif) receptor 3 |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 40665.65 |
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| Organism: | Homo sapiens (Human) |
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| Description: | n/a |
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| Residue: | 368 |
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| Sequence: | MVLEVSDHQVLNDAEVAALLENFSSSYDYGENESDSCCTSPPCPQDFSLNFDRAFLPALY
SLLFLLGLLGNGAVAAVLLSRRTALSSTDTFLLHLAVADTLLVLTLPLWAVDAAVQWVFG
SGLCKVAGALFNINFYAGALLLACISFDRYLNIVHATQLYRRGPPARVTLTCLAVWGLCL
LFALPDFIFLSAHHDERLNATHCQYNFPQVGRTALRVLQLVAGFLLPLLVMAYCYAHILA
VLLVSRGQRRLRAMRLVVVVVVAFALCWTPYHLVVLVDILMDLGALARNCGRESRVDVAK
SVTSGLGYMHCCLNPLLYAFVGVKFRERMWMLLLRLGCPNQRGLQRQPSSSRRDSSWSET
SEASYSGL
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| BDBM50595462 |
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| n/a |
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| Name | BDBM50595462 |
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| Synonyms: | CHEMBL5172352 |
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| Type | Small organic molecule |
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| Emp. Form. | C25H25F3N6O3S |
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| Mol. Mass. | 546.565 |
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| SMILES | CCOc1ncc(cn1)-c1nc(sc1N1CCN([C@H](C)C1)C(=O)CN1C(=O)Cc2ccccc12)C(F)(F)F |r| |
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| Structure | 
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