| Reaction Details |
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 | Report a problem with these data |
| Target | 5-hydroxytryptamine receptor 2A |
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| Ligand | BDBM50171890 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_303813 (CHEMBL827072) |
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| Ki | >100000±n/a nM |
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| Citation |  Fiorino, F; Perissutti, E; Severino, B; Santagada, V; Cirillo, D; Terracciano, S; Massarelli, P; Bruni, G; Collavoli, E; Renner, C; Caliendo, G New 5-hydroxytryptamine(1A) receptor ligands containing a norbornene nucleus: synthesis and in vitro pharmacological evaluation. J Med Chem48:5495-503 (2005) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| 5-hydroxytryptamine receptor 2A |
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| Name: | 5-hydroxytryptamine receptor 2A |
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| Synonyms: | 5-HT-2A | 5-HT2 | 5-HT2A | 5-hydroxytryptamine receptor 2A (5-HT2A) | 5-hydroxytryptamine receptor 2A (5HT2A) | 5HT2A_RAT | Htr2 | Htr2a | Serotonin Receptor 2A |
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| Type: | G Protein-Coupled Receptor (GPCR) |
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| Mol. Mass.: | 52852.05 |
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| Organism: | Rattus norvegicus (rat) |
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| Description: | Rat cortex membranes 5-HT2A receptors. |
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| Residue: | 471 |
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| Sequence: | MEILCEDNISLSSIPNSLMQLGDGPRLYHNDFNSRDANTSEASNWTIDAENRTNLSCEGY
LPPTCLSILHLQEKNWSALLTTVVIILTIAGNILVIMAVSLEKKLQNATNYFLMSLAIAD
MLLGFLVMPVSMLTILYGYRWPLPSKLCAIWIYLDVLFSTASIMHLCAISLDRYVAIQNP
IHHSRFNSRTKAFLKIIAVWTISVGISMPIPVFGLQDDSKVFKEGSCLLADDNFVLIGSF
VAFFIPLTIMVITYFLTIKSLQKEATLCVSDLSTRAKLASFSFLPQSSLSSEKLFQRSIH
REPGSYAGRRTMQSISNEQKACKVLGIVFFLFVVMWCPFFITNIMAVICKESCNENVIGA
LLNVFVWIGYLSSAVNPLVYTLFNKTYRSAFSRYIQCQYKENRKPLQLILVNTIPALAYK
SSQLQVGQKKNSQEDAEQTVDDCSMVTLGKQQSEENCTDNIETVNEKVSCV
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| BDBM50171890 |
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| n/a |
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| Name | BDBM50171890 |
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| Synonyms: | 4-{2-[4-(2-Chloro-phenyl)-piperazin-1-yl]-ethoxy}-4-aza-tricyclo[5.2.1.0*2,6*]dec-8-ene-3,5-dione | CHEMBL426813 |
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| Type | Small organic molecule |
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| Emp. Form. | C21H24ClN3O3 |
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| Mol. Mass. | 401.887 |
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| SMILES | Clc1ccccc1N1CCN(CCON2C(=O)C3C4CC(C=C4)C3C2=O)CC1 |c:22| |
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| Structure | 
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