| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Synaptic vesicular amine transporter |
|---|
| Ligand | BDBM50172083 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_320944 (CHEMBL882463) |
|---|
| Ki | >100000±n/a nM |
|---|
| Citation |  Zheng, G; Dwoskin, LP; Deaciuc, AG; Crooks, PA Synthesis and evaluation of a series of tropane analogues as novel vesicular monoamine transporter-2 ligands. Bioorg Med Chem Lett15:4463-6 (2005) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Synaptic vesicular amine transporter |
|---|
| Name: | Synaptic vesicular amine transporter |
|---|
| Synonyms: | Monoamine transporter | Slc18a2 | Solute carrier family 18 member 2 | Svat | Synaptic vesicular amine transporter | VAT2 | VMAT2_RAT | Vesicular amine transporter 2 | Vesicular monoamine transporter 2 (VMAT2) | Vmat2 |
|---|
| Type: | Protein |
|---|
| Mol. Mass.: | 55689.58 |
|---|
| Organism: | Rattus norvegicus (Rat) |
|---|
| Description: | Q01827 |
|---|
| Residue: | 515 |
|---|
| Sequence: | MALSDLVLLRWLRDSRHSRKLILFIVFLALLLDNMLLTVVVPIIPSYLYSIKHEKNSTEI
QTTRPELVVSTSESIFSYYNNSTVLITGNATGTLPGGQSHKATSTQHTVANTTVPSDCPS
EDRDLLNENVQVGLLFASKATVQLLTNPFIGLLTNRIGYPIPMFAGFCIMFISTVMFAFS
SSYAFLLIARSLQGIGSSCSSVAGMGMLASVYTDDEERGKPMGIALGGLAMGVLVGPPFG
SVLYEFVGKTAPFLVLAALVLLDGAIQLFVLQPSRVQPESQKGTPLTTLLKDPYILIAAG
SICFANMGIAMLEPALPIWMMETMCSRKWQLGVAFLPASISYLIGTNIFGILAHKMGRWL
CALLGMVIVGISILCIPFAKNIYGLIAPNFGVGFAIGMVDSSMMPIMGYLVDLRHVSVYG
SVYAIADVAFCMGYAIGPSAGGAIAKAIGFPWLMTIIGIIDIAFAPLCFFLRSPPAKEEK
MAILMDHNCPIKRKMYTQNNVQSYPIGDDEESESD
|
|
|
|---|
| BDBM50172083 |
|---|
| n/a |
|---|
| Name | BDBM50172083 |
|---|
| Synonyms: | (2S,4R)-2,4-Dibenzyl-8-methyl-8-aza-bicyclo[3.2.1]octan-3-ol | CHEMBL382976 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C22H27NO |
|---|
| Mol. Mass. | 321.4559 |
|---|
| SMILES | CN1C2CCC1[C@@H](Cc1ccccc1)C(O)[C@H]2Cc1ccccc1 |THB:17:16:1:3.4,7:6:1:3.4,15:14:1:3.4| |
|---|
| Structure | 
|
|---|
Search and Browse
