| Reaction Details |
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 | Report a problem with these data |
| Target | G-protein coupled receptor 39 |
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| Ligand | BDBM50596622 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_2221584 (CHEMBL5134918) |
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| EC50 | 641±n/a nM |
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| Citation |  Burley, R; Hewer, RC; Teall, M; Dickson, L; Ossola, B; Russell, S; Bender, C; Cheung, T; Powell, JAC; Xu, X; Brice, NL; Otter, L; Arimont, M; Kidd, SL; Vidal, D; Dale, JW; Mervin, L; Sore, HF; Mateu, N; Lakshminarayana, N; Dawson, LA; Carlton, M; Bürli, RW Synthesis and SAR of novel GPR39 agonists and positive allosteric modulators. Bioorg Med Chem Lett61:0 (2022) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| G-protein coupled receptor 39 |
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| Name: | G-protein coupled receptor 39 |
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| Synonyms: | GPR39 | GPR39_HUMAN |
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| Type: | PROTEIN |
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| Mol. Mass.: | 51351.94 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_107977 |
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| Residue: | 453 |
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| Sequence: | MASPSLPGSDCSQIIDHSHVPEFEVATWIKITLILVYLIIFVMGLLGNSATIRVTQVLQK
KGYLQKEVTDHMVSLACSDILVFLIGMPMEFYSIIWNPLTTSSYTLSCKLHTFLFEACSY
ATLLHVLTLSFERYIAICHPFRYKAVSGPCQVKLLIGFVWVTSALVALPLLFAMGTEYPL
VNVPSHRGLTCNRSSTRHHEQPETSNMSICTNLSSRWTVFQSSIFGAFVVYLVVLLSVAF
MCWNMMQVLMKSQKGSLAGGTRPPQLRKSESEESRTARRQTIIFLRLIVVTLAVCWMPNQ
IRRIMAAAKPKHDWTRSYFRAYMILLPFSETFFYLSSVINPLLYTVSSQQFRRVFVQVLC
CRLSLQHANHEKRLRVHAHSTTDSARFVQRPLLFASRRQSSARRTEKIFLSTFQSEAEPQ
SKSQSLSLESLEPNSGAKPANSAAENGFQEHEV
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| BDBM50596622 |
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| n/a |
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| Name | BDBM50596622 |
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| Synonyms: | CHEMBL5203229 |
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| Type | Small organic molecule |
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| Emp. Form. | C22H23N5O2 |
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| Mol. Mass. | 389.4503 |
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| SMILES | Cn1cc(cn1)-c1ccc2nc([nH]c(=O)c2c1)C(N)CCOCc1ccccc1 |
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| Structure | 
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