| Reaction Details |
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 | Report a problem with these data |
| Target | P2X purinoceptor 5 |
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| Ligand | BDBM50596630 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_2221596 (CHEMBL5134930) |
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| IC50 | 9037±n/a nM |
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| Citation |  Mahmood, A; Ali Shah, SJ; Iqbal, J Design and synthesis of adamantane-1-carbonyl thiourea derivatives as potent and selective inhibitors of h-P2X4 and h-P2X7 receptors: An Emerging therapeutic tool for treatment of inflammation and neurological disorders. Eur J Med Chem231:0 (2022) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| P2X purinoceptor 5 |
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| Name: | P2X purinoceptor 5 |
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| Synonyms: | ATP receptor | P2RX5 | P2RX5_HUMAN | P2X5 | Purinergic receptor |
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| Type: | PROTEIN |
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| Mol. Mass.: | 47208.74 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_612725 |
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| Residue: | 422 |
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| Sequence: | MGQAGCKGLCLSLFDYKTEKYVIAKNKKVGLLYRLLQASILAYLVVWVFLIKKGYQDVDT
SLQSAVITKVKGVAFTNTSDLGQRIWDVADYVIPAQGENVFFVVTNLIVTPNQRQNVCAE
NEGIPDGACSKDSDCHAGEAVTAGNGVKTGRCLRRENLARGTCEIFAWCPLETSSRPEEP
FLKEAEDFTIFIKNHIRFPKFNFSKSNVMDVKDRSFLKSCHFGPKNHYCPIFRLGSVIRW
AGSDFQDIALEGGVIGINIEWNCDLDKAASECHPHYSFSRLDNKLSKSVSSGYNFRFARY
YRDAAGVEFRTLMKAYGIRFDVMVNGKGAFFCDLVLIYLIKKREFYRDKKYEEVRGLEDS
SQEAEDEASGLGLSEQLTSGPGLLGMPEQQELQEPPEAKRGSSSQKGNGSVCPQLLEPHR
ST
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| BDBM50596630 |
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| n/a |
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| Name | BDBM50596630 |
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| Synonyms: | CHEMBL5172961 |
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| Type | Small organic molecule |
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| Emp. Form. | C19H23BrN2OS |
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| Mol. Mass. | 407.368 |
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| SMILES | Cc1ccc(NC(=S)NC(=O)C23CC4CC(CC(C4)C2)C3)c(Br)c1 |TLB:18:17:20:14.13.12,18:13:20:17.19.16,THB:16:17:20.15.14:12,16:15:17.19.18:12| |
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| Structure | 
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