| Reaction Details |
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 | Report a problem with these data |
| Target | Somatostatin receptor type 4 |
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| Ligand | BDBM50597587 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_2223692 (CHEMBL5137205) |
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| Ki | 0.500000±n/a nM |
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| Citation |  Neumann, WL; Sandoval, KE; Mobayen, S; Minaeian, M; Kukielski, SG; Srabony, KN; Frare, R; Slater, O; Farr, SA; Niehoff, ML; Hospital, A; Kontoyianni, M; Crider, AM; Witt, KA Synthesis and structure-activity relationships of 3,4,5-trisubstituted-1,2,4-triazoles: high affinity and selective somatostatin receptor-4 agonists for Alzheimer's disease treatment. RSC Med Chem12:1352-1365 (2021) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Somatostatin receptor type 4 |
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| Name: | Somatostatin receptor type 4 |
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| Synonyms: | SOMATOSTATIN SST4 | SS-4-R | SS4-R | SS4R | SSR4_HUMAN | SST4R | SSTR4 | Somatostatin receptor type 4 (SSTR4) |
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| Type: | Enzyme |
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| Mol. Mass.: | 42015.38 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P31391 |
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| Residue: | 388 |
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| Sequence: | MSAPSTLPPGGEEGLGTAWPSAANASSAPAEAEEAVAGPGDARAAGMVAIQCIYALVCLV
GLVGNALVIFVILRYAKMKTATNIYLLNLAVADELFMLSVPFVASSAALRHWPFGSVLCR
AVLSVDGLNMFTSVFCLTVLSVDRYVAVVHPLRAATYRRPSVAKLINLGVWLASLLVTLP
IAIFADTRPARGGQAVACNLQWPHPAWSAVFVVYTFLLGFLLPVLAIGLCYLLIVGKMRA
VALRAGWQQRRRSEKKITRLVLMVVVVFVLCWMPFYVVQLLNLFVTSLDATVNHVSLILS
YANSCANPILYGFLSDNFRRFFQRVLCLRCCLLEGAGGAEEEPLDYYATALKSKGGAGCM
CPPLPCQQEALQPEPGRKRIPLTRTTTF
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| BDBM50597587 |
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| n/a |
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| Name | BDBM50597587 |
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| Synonyms: | CHEMBL5174969 |
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| Type | Small organic molecule |
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| Emp. Form. | C24H22ClFN6 |
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| Mol. Mass. | 448.923 |
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| SMILES | Fc1ccc2c(Cc3nnc(Cc4cccc(Cl)c4)n3CCCc3c[nH]cn3)c[nH]c2c1 |
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| Structure | 
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