| Reaction Details |
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 | Report a problem with these data |
| Target | Somatostatin receptor type 1 |
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| Ligand | BDBM523767 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_2223693 (CHEMBL5137206) |
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| Ki | 468±n/a nM |
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| Citation |  Neumann, WL; Sandoval, KE; Mobayen, S; Minaeian, M; Kukielski, SG; Srabony, KN; Frare, R; Slater, O; Farr, SA; Niehoff, ML; Hospital, A; Kontoyianni, M; Crider, AM; Witt, KA Synthesis and structure-activity relationships of 3,4,5-trisubstituted-1,2,4-triazoles: high affinity and selective somatostatin receptor-4 agonists for Alzheimer's disease treatment. RSC Med Chem12:1352-1365 (2021) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Somatostatin receptor type 1 |
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| Name: | Somatostatin receptor type 1 |
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| Synonyms: | SOMATOSTATIN SST1 | SRIF-2 | SS-1-R | SS1-R | SS1R | SSR1_HUMAN | SSTR1 | Somatostatin receptor type 1 (SSTR1) |
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| Type: | Enzyme |
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| Mol. Mass.: | 42692.81 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P30872 |
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| Residue: | 391 |
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| Sequence: | MFPNGTASSPSSSPSPSPGSCGEGGGSRGPGAGAADGMEEPGRNASQNGTLSEGQGSAIL
ISFIYSVVCLVGLCGNSMVIYVILRYAKMKTATNIYILNLAIADELLMLSVPFLVTSTLL
RHWPFGALLCRLVLSVDAVNMFTSIYCLTVLSVDRYVAVVHPIKAARYRRPTVAKVVNLG
VWVLSLLVILPIVVFSRTAANSDGTVACNMLMPEPAQRWLVGFVLYTFLMGFLLPVGAIC
LCYVLIIAKMRMVALKAGWQQRKRSERKITLMVMMVVMVFVICWMPFYVVQLVNVFAEQD
DATVSQLSVILGYANSCANPILYGFLSDNFKRSFQRILCLSWMDNAAEEPVDYYATALKS
RAYSVEDFQPENLESGGVFRNGTCTSRITTL
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| BDBM523767 |
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| n/a |
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| Name | BDBM523767 |
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| Synonyms: | US11136312, Compound SK-I-91 |
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| Type | Small organic molecule |
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| Emp. Form. | C24H22F2N6 |
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| Mol. Mass. | 432.4685 |
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| SMILES | Fc1ccc(Cc2nnc(Cc3c[nH]c4cc(F)ccc34)n2CCCc2c[nH]cn2)cc1 |
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| Structure | 
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