| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Melanocortin receptor 4 |
|---|
| Ligand | BDBM50174238 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_326843 (CHEMBL860438) |
|---|
| Ki | 110±n/a nM |
|---|
| Citation |  Pontillo, J; Tran, JA; White, NS; Arellano, M; Fleck, BA; Marinkovic, D; Tucci, FC; Saunders, J; Foster, AC; Chen, C Structure-activity relationship studies on a series of cyclohexylpiperazines bearing a phanylacetamide as ligands of the human melanocortin-4 receptor. Bioorg Med Chem Lett15:5237-40 (2005) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Melanocortin receptor 4 |
|---|
| Name: | Melanocortin receptor 4 |
|---|
| Synonyms: | MC4-R | MC4R | MC4R_HUMAN | Melanocortin MC4 | Melanocortin receptor 4 (MC-4) | Melanocortin receptor 4 (MC4-R) | Melanocortin receptor 4 (MC4R) |
|---|
| Type: | Enzyme |
|---|
| Mol. Mass.: | 36949.50 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | P32245 |
|---|
| Residue: | 332 |
|---|
| Sequence: | MVNSTHRGMHTSLHLWNRSSYRLHSNASESLGKGYSDGGCYEQLFVSPEVFVTLGVISLL
ENILVIVAIAKNKNLHSPMYFFICSLAVADMLVSVSNGSETIVITLLNSTDTDAQSFTVN
IDNVIDSVICSSLLASICSLLSIAVDRYFTIFYALQYHNIMTVKRVGIIISCIWAACTVS
GILFIIYSDSSAVIICLITMFFTMLALMASLYVHMFLMARLHIKRIAVLPGTGAIRQGAN
MKGAITLTILIGVFVVCWAPFFLHLIFYISCPQNPYCVCFMSHFNLYLILIMCNSIIDPL
IYALRSQELRKTFKEIICCYPLGGLCDLSSRY
|
|
|
|---|
| BDBM50174238 |
|---|
| n/a |
|---|
| Name | BDBM50174238 |
|---|
| Synonyms: | CHEMBL371683 | N-(1-{4-[(R)-2-acetylamino-3-(4-chloro-phenyl)-propionyl]-piperazin-1-yl}-cyclohexylmethyl)-2-phenyl-acetamide |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C30H39ClN4O3 |
|---|
| Mol. Mass. | 539.109 |
|---|
| SMILES | CC(=O)N[C@H](Cc1ccc(Cl)cc1)C(=O)N1CCN(CC1)C1(CNC(=O)Cc2ccccc2)CCCCC1 |
|---|
| Structure | 
|
|---|
Search and Browse
