| Reaction Details |
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 | Report a problem with these data |
| Target | Motilin receptor |
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| Ligand | BDBM50599720 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_2231450 (CHEMBL5145222) |
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| EC50 | 0.970000±n/a nM |
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| Citation |  Toda, N; Shida, T; Takano, R; Katagiri, T; Hirouchi, M; Abe, M; Soma, K; Nakagami, Y; Yamazaki, M Discovery of DS-3801b, a non-macrolide GPR38 agonist with N-methylanilide structure. Bioorg Med Chem Lett59:0 (2022) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Motilin receptor |
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| Name: | Motilin receptor |
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| Synonyms: | G-protein coupled receptor 38 | GPR38 | MLNR | MTLR | MTLR1 | MTLR_HUMAN |
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| Type: | PROTEIN |
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| Mol. Mass.: | 45365.95 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_122664 |
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| Residue: | 412 |
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| Sequence: | MGSPWNGSDGPEGAREPPWPALPPCDERRCSPFPLGALVPVTAVCLCLFVVGVSGNVVTV
MLIGRYRDMRTTTNLYLGSMAVSDLLILLGLPFDLYRLWRSRPWVFGPLLCRLSLYVGEG
CTYATLLHMTALSVERYLAICRPLRARVLVTRRRVRALIAVLWAVALLSAGPFLFLVGVE
QDPGISVVPGLNGTARIASSPLASSPPLWLSRAPPPSPPSGPETAEAAALFSRECRPSPA
QLGALRVMLWVTTAYFFLPFLCLSILYGLIGRELWSSRRPLRGPAASGRERGHRQTVRVL
LVVVLAFIICWLPFHVGRIIYINTEDSRMMYFSQYFNIVALQLFYLSASINPILYNLISK
KYRAAAFKLLLARKSRPRGFHRSRDTAGEVAGDTGGDTVGYTETSANVKTMG
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| BDBM50599720 |
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| n/a |
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| Name | BDBM50599720 |
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| Synonyms: | CHEMBL525634 | H-Motilin |
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| Type | Small organic molecule |
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| Emp. Form. | C120H188N34O35S |
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| Mol. Mass. | 2699.049 |
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| SMILES | CC[C@H](C)[C@H](NC(=O)[C@@H]1CCCN1C(=O)[C@@H](NC(=O)[C@@H](N)Cc1ccccc1)C(C)C)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)NCC(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCSC)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CCCCN)C(=O)NCC(=O)N[C@@H](CCC(N)=O)C(O)=O |r| |
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| Structure | 
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