Ki Summary

Reaction Details

Report a problem with these data

Target

Motilin receptor

Ligand

BDBM50599735

Substrate/Competitor

n/a

Meas. Tech.

ChEMBL_2231450 (CHEMBL5145222)

EC50

2.6±n/a nM

Citation

Toda, N; Shida, T; Takano, R; Katagiri, T; Hirouchi, M; Abe, M; Soma, K; Nakagami, Y; Yamazaki, M Discovery of DS-3801b, a non-macrolide GPR38 agonist with N-methylanilide structure. Bioorg Med Chem Lett59:0 (2022) [PubMed] Article

More Info.:

Get all data from this article, Assay Method

Motilin receptor

Name:

Motilin receptor

Synonyms:

Type:

PROTEIN

Mol. Mass.:

45365.95

Organism:

Homo sapiens (Human)

Description:

ChEMBL_122664

Residue:

412

Sequence:

MGSPWNGSDGPEGAREPPWPALPPCDERRCSPFPLGALVPVTAVCLCLFVVGVSGNVVTV
MLIGRYRDMRTTTNLYLGSMAVSDLLILLGLPFDLYRLWRSRPWVFGPLLCRLSLYVGEG
CTYATLLHMTALSVERYLAICRPLRARVLVTRRRVRALIAVLWAVALLSAGPFLFLVGVE
QDPGISVVPGLNGTARIASSPLASSPPLWLSRAPPPSPPSGPETAEAAALFSRECRPSPA
QLGALRVMLWVTTAYFFLPFLCLSILYGLIGRELWSSRRPLRGPAASGRERGHRQTVRVL
LVVVLAFIICWLPFHVGRIIYINTEDSRMMYFSQYFNIVALQLFYLSASINPILYNLISK
KYRAAAFKLLLARKSRPRGFHRSRDTAGEVAGDTGGDTVGYTETSANVKTMG

BDBM50599735

n/a

Name

BDBM50599735

Synonyms:

CHEMBL5192584

Type

Small organic molecule

Emp. Form.

C30H44N4O2

Mol. Mass.

492.696

SMILES

CCOCc1cccc(N[C@H]2CC[C@@H](CC2)C(=O)N(C)c2ccc(CN3CCN[C@@H](C)C3)c(C)c2)c1 |r,wU:13.16,29.30,wD:10.9,(8.67,3.47,;7.33,2.7,;6,3.47,;4.67,2.7,;3.33,3.47,;3.33,5,;2,5.77,;.66,5.01,;.66,3.47,;-.67,2.7,;-.67,1.16,;-2,.39,;-2,-1.15,;-.67,-1.92,;.66,-1.15,;.66,.39,;-.67,-3.46,;.66,-4.23,;-2,-4.23,;-2,-5.77,;-3.34,-3.46,;-3.34,-1.92,;-4.67,-1.15,;-6,-1.92,;-7.33,-1.15,;-7.33,.39,;-8.67,1.16,;-8.67,2.7,;-7.33,3.47,;-6,2.7,;-4.67,3.47,;-6,1.16,;-6,-3.47,;-7.33,-4.24,;-4.66,-4.23,;2,2.69,)|

Structure