| Reaction Details |
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 | Report a problem with these data |
| Target | D(3) dopamine receptor |
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| Ligand | BDBM50599877 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_2231894 (CHEMBL5145666) |
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| Ki | 948±n/a nM |
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| Citation |  Tolentino, KT; Mashinson, V; Vadukoot, AK; Hopkins, CR Discovery and characterization of benzyloxy piperidine based dopamine 4 receptor antagonists. Bioorg Med Chem Lett61:0 (2022) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| D(3) dopamine receptor |
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| Name: | D(3) dopamine receptor |
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| Synonyms: | DRD3 | DRD3_HUMAN | Dopamine D3 receptor |
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| Type: | PROTEIN |
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| Mol. Mass.: | 44213.40 |
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| Organism: | Homo sapiens |
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| Description: | ChEMBL_105671 |
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| Residue: | 400 |
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| Sequence: | MASLSQLSGHLNYTCGAENSTGASQARPHAYYALSYCALILAIVFGNGLVCMAVLKERAL
QTTTNYLVVSLAVADLLVATLVMPWVVYLEVTGGVWNFSRICCDVFVTLDVMMCTASILN
LCAISIDRYTAVVMPVHYQHGTGQSSCRRVALMITAVWVLAFAVSCPLLFGFNTTGDPTV
CSISNPDFVIYSSVVSFYLPFGVTVLVYARIYVVLKQRRRKRILTRQNSQCNSVRPGFPQ
QTLSPDPAHLELKRYYSICQDTALGGPGFQERGGELKREEKTRNSLSPTIAPKLSLEVRK
LSNGRLSTSLKLGPLQPRGVPLREKKATQMVAIVLGAFIVCWLPFFLTHVLNTHCQTCHV
SPELYSATTWLGYVNSALNPVIYTTFNIEFRKAFLKILSC
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| BDBM50599877 |
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| n/a |
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| Name | BDBM50599877 |
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| Synonyms: | CHEMBL5182602 |
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| Type | Small organic molecule |
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| Emp. Form. | C21H22F3N3O |
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| Mol. Mass. | 389.4141 |
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| SMILES | FC(F)(F)c1cccc(COC2CCN(Cc3ccc4[nH]cnc4c3)CC2)c1 |
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| Structure | 
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