| Reaction Details |
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 | Report a problem with these data |
| Target | Adenosine receptor A3 |
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| Ligand | BDBM50179182 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_325330 (CHEMBL860165) |
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| Ki | 103±n/a nM |
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| Citation |  Jacobson, KA; Gao, ZG; Tchilibon, S; Duong, HT; Joshi, BV; Sonin, D; Liang, BT Semi-rational design of (north)-methanocarba nucleosides as dual acting A(1) and A(3) adenosine receptor agonists: novel prototypes for cardioprotection. J Med Chem48:8103-7 (2005) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Adenosine receptor A3 |
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| Name: | Adenosine receptor A3 |
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| Synonyms: | AA3R_RAT | Adenosine A3 receptor | Adenosine receptor A2a and A3 | Adora3 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 36643.73 |
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| Organism: | Rattus norvegicus |
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| Description: | ChEMBL_479910 |
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| Residue: | 320 |
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| Sequence: | MKANNTTTSALWLQITYITMEAAIGLCAVVGNMLVIWVVKLNRTLRTTTFYFIVSLALAD
IAVGVLVIPLAIAVSLEVQMHFYACLFMSCVLLVFTHASIMSLLAIAVDRYLRVKLTVRY
RTVTTQRRIWLFLGLCWLVSFLVGLTPMFGWNRKVTLELSQNSSTLSCHFRSVVGLDYMV
FFSFITWILIPLVVMCIIYLDIFYIIRNKLSQNLTGFRETRAFYGREFKTAKSLFLVLFL
FALCWLPLSIINFVSYFNVKIPEIAMCLGILLSHANSMMNPIVYACKIKKFKETYFVILR
ACRLCQTSDSLDSNLEQTTE
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| BDBM50179182 |
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| n/a |
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| Name | BDBM50179182 |
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| Synonyms: | (2R,3R,4S,5R)-2-(6-(bicyclo[2.2.1]heptan-7-ylamino)-9H-purin-9-yl)-5-(hydroxymethyl)-tetrahydrofuran-3,4-diol | CHEMBL176551 |
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| Type | Small organic molecule |
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| Emp. Form. | C17H23N5O4 |
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| Mol. Mass. | 361.3956 |
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| SMILES | OC[C@H]1O[C@H]([C@H](O)[C@@H]1O)n1cnc2c(NC3C4CCC3CC4)ncnc12 |
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| Structure | 
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