| Reaction Details |
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 | Report a problem with these data |
| Target | Peroxisome proliferator-activated receptor delta |
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| Ligand | BDBM50179822 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_339275 (CHEMBL867228) |
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| IC50 | 1350±n/a nM |
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| Citation |  Desai, RC; Metzger, E; Santini, C; Meinke, PT; Heck, JV; Berger, JP; MacNaul, KL; Cai, TQ; Wright, SD; Agrawal, A; Moller, DE; Sahoo, SP Design and synthesis of potent and subtype-selective PPARalpha agonists. Bioorg Med Chem Lett16:1673-8 (2006) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Peroxisome proliferator-activated receptor delta |
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| Name: | Peroxisome proliferator-activated receptor delta |
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| Synonyms: | NR1C2 | NUC1 | NUCI | Nuclear hormone receptor 1 | Nuclear receptor subfamily 1 group C member 2 | PPAR delta | PPAR-beta | PPARB | PPARD | PPARD_HUMAN | Peroxisome proliferator-activated receptor | Peroxisome proliferator-activated receptor beta | Peroxisome proliferator-activated receptor delta |
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| Type: | Enzyme |
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| Mol. Mass.: | 49910.45 |
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| Organism: | Homo sapiens (Human) |
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| Description: | Q03181 |
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| Residue: | 441 |
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| Sequence: | MEQPQEEAPEVREEEEKEEVAEAEGAPELNGGPQHALPSSSYTDLSRSSSPPSLLDQLQM
GCDGASCGSLNMECRVCGDKASGFHYGVHACEGCKGFFRRTIRMKLEYEKCERSCKIQKK
NRNKCQYCRFQKCLALGMSHNAIRFGRMPEAEKRKLVAGLTANEGSQYNPQVADLKAFSK
HIYNAYLKNFNMTKKKARSILTGKASHTAPFVIHDIETLWQAEKGLVWKQLVNGLPPYKE
ISVHVFYRCQCTTVETVRELTEFAKSIPSFSSLFLNDQVTLLKYGVHEAIFAMLASIVNK
DGLLVANGSGFVTREFLRSLRKPFSDIIEPKFEFAVKFNALELDDSDLALFIAAIILCGD
RPGLMNVPRVEAIQDTILRALEFHLQANHPDAQYLFPKLLQKMADLRQLVTEHAQMMQRI
KKTETETSLHPLLQEIYKDMY
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| BDBM50179822 |
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| n/a |
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| Name | BDBM50179822 |
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| Synonyms: | 3-(4-(3-(2-chloro-4-(4-fluorophenoxy)phenoxy)propoxy)phenyl)-2-cyclobutylpropanoic acid | CHEMBL383011 |
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| Type | Small organic molecule |
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| Emp. Form. | C28H28ClFO5 |
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| Mol. Mass. | 498.97 |
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| SMILES | OC(=O)C(Cc1ccc(OCCCOc2ccc(Oc3ccc(F)cc3)cc2Cl)cc1)C1CCC1 |
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| Structure | 
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