| Reaction Details |
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 | Report a problem with these data |
| Target | Type-1 angiotensin II receptor |
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| Ligand | BDBM50600589 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_2234591 (CHEMBL5148363) |
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| Ki | >3000±n/a nM |
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| Citation |  Roy, T; Petersen, NN; Gopalan, G; Gising, J; Hallberg, M; Larhed, M 2-Alkyl substituted benzimidazoles as a new class of selective AT2 receptor ligands. Bioorg Med Chem66:0 (2022) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Type-1 angiotensin II receptor |
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| Name: | Type-1 angiotensin II receptor |
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| Synonyms: | AGTR1 | AGTR1A | AGTR1B | AGTR1_HUMAN | AT1 | AT1AR | AT1BR | AT2R1 | AT2R1B | Angiotensin II AT1 | Angiotensin II receptor | Angiotensin II type 1b (AT-1b) receptor | Type-1 angiotensin II receptor (AT1) |
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| Type: | Protein |
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| Mol. Mass.: | 41080.75 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P30556 |
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| Residue: | 359 |
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| Sequence: | MILNSSTEDGIKRIQDDCPKAGRHNYIFVMIPTLYSIIFVVGIFGNSLVVIVIYFYMKLK
TVASVFLLNLALADLCFLLTLPLWAVYTAMEYRWPFGNYLCKIASASVSFNLYASVFLLT
CLSIDRYLAIVHPMKSRLRRTMLVAKVTCIIIWLLAGLASLPAIIHRNVFFIENTNITVC
AFHYESQNSTLPIGLGLTKNILGFLFPFLIILTSYTLIWKALKKAYEIQKNKPRNDDIFK
IIMAIVLFFFFSWIPHQIFTFLDVLIQLGIIRDCRIADIVDTAMPITICIAYFNNCLNPL
FYGFLGKKFKRYFLQLLKYIPPKAKSHSNLSTKMSTLSYRPSDNVSSSTKKPAPCFEVE
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| BDBM50600589 |
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| n/a |
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| Name | BDBM50600589 |
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| Synonyms: | CHEMBL5202149 |
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| Type | Small organic molecule |
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| Emp. Form. | C32H34F5N3O4S |
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| Mol. Mass. | 651.687 |
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| SMILES | CCCc1ccc(c(c1)-c1cc(F)c(Cn2c(nc3ccccc23)C(C)(C)C)c(F)c1)S(=O)(=O)NC(=O)OCCCC(F)(F)F |
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| Structure | 
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