| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Type-2 angiotensin II receptor |
|---|
| Ligand | BDBM50600571 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_2234592 (CHEMBL5148364) |
|---|
| Ki | 29±n/a nM |
|---|
| Citation |  Roy, T; Petersen, NN; Gopalan, G; Gising, J; Hallberg, M; Larhed, M 2-Alkyl substituted benzimidazoles as a new class of selective AT2 receptor ligands. Bioorg Med Chem66:0 (2022) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Type-2 angiotensin II receptor |
|---|
| Name: | Type-2 angiotensin II receptor |
|---|
| Synonyms: | AGTR2 | AGTR2_HUMAN | AT2 | Angiotensin II receptor | Angiotensin II type 2 (AT-2) receptor | Angiotensin II, central | Type-2 angiotensin II receptor |
|---|
| Type: | Enzyme Catalytic Domain |
|---|
| Mol. Mass.: | 41201.61 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | Angiotensin II, central 0 0::P50052 |
|---|
| Residue: | 363 |
|---|
| Sequence: | MKGNSTLATTSKNITSGLHFGLVNISGNNESTLNCSQKPSDKHLDAIPILYYIIFVIGFL
VNIVVVTLFCCQKGPKKVSSIYIFNLAVADLLLLATLPLWATYYSYRYDWLFGPVMCKVF
GSFLTLNMFASIFFITCMSVDRYQSVIYPFLSQRRNPWQASYIVPLVWCMACLSSLPTFY
FRDVRTIEYLGVNACIMAFPPEKYAQWSAGIALMKNILGFIIPLIFIATCYFGIRKHLLK
TNSYGKNRITRDQVLKMAAAVVLAFIICWLPFHVLTFLDALAWMGVINSCEVIAVIDLAL
PFAILLGFTNSCVNPFLYCFVGNRFQQKLRSVFRVPITWLQGKRESMSCRKSSSLREMET
FVS
|
|
|
|---|
| BDBM50600571 |
|---|
| n/a |
|---|
| Name | BDBM50600571 |
|---|
| Synonyms: | CHEMBL5179052 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C28H31N3O4S |
|---|
| Mol. Mass. | 505.628 |
|---|
| SMILES | CCCCOC(=O)NS(=O)(=O)c1ccc(CCC)cc1-c1ccc(Cn2cnc3ccccc23)cc1 |
|---|
| Structure | 
|
|---|
Search and Browse
