| Reaction Details |
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 | Report a problem with these data |
| Target | Type-2 angiotensin II receptor |
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| Ligand | BDBM50600591 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_2234592 (CHEMBL5148364) |
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| Ki | 6.0±n/a nM |
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| Citation |  Roy, T; Petersen, NN; Gopalan, G; Gising, J; Hallberg, M; Larhed, M 2-Alkyl substituted benzimidazoles as a new class of selective AT2 receptor ligands. Bioorg Med Chem66:0 (2022) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Type-2 angiotensin II receptor |
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| Name: | Type-2 angiotensin II receptor |
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| Synonyms: | AGTR2 | AGTR2_HUMAN | AT2 | Angiotensin II receptor | Angiotensin II type 2 (AT-2) receptor | Angiotensin II, central | Type-2 angiotensin II receptor |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 41201.61 |
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| Organism: | Homo sapiens (Human) |
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| Description: | Angiotensin II, central 0 0::P50052 |
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| Residue: | 363 |
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| Sequence: | MKGNSTLATTSKNITSGLHFGLVNISGNNESTLNCSQKPSDKHLDAIPILYYIIFVIGFL
VNIVVVTLFCCQKGPKKVSSIYIFNLAVADLLLLATLPLWATYYSYRYDWLFGPVMCKVF
GSFLTLNMFASIFFITCMSVDRYQSVIYPFLSQRRNPWQASYIVPLVWCMACLSSLPTFY
FRDVRTIEYLGVNACIMAFPPEKYAQWSAGIALMKNILGFIIPLIFIATCYFGIRKHLLK
TNSYGKNRITRDQVLKMAAAVVLAFIICWLPFHVLTFLDALAWMGVINSCEVIAVIDLAL
PFAILLGFTNSCVNPFLYCFVGNRFQQKLRSVFRVPITWLQGKRESMSCRKSSSLREMET
FVS
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| BDBM50600591 |
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| n/a |
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| Name | BDBM50600591 |
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| Synonyms: | CHEMBL5174301 |
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| Type | Small organic molecule |
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| Emp. Form. | C32H34F5N3O4S |
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| Mol. Mass. | 651.687 |
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| SMILES | CCCc1ccc(c(c1)-c1ccc(Cn2c(nc3ccccc23)C(C)(C)C)cc1)S(=O)(=O)NC(=O)OCCC(F)(F)C(F)(F)F |
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| Structure | 
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