| Reaction Details |
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 | Report a problem with these data |
| Target | Cholesterol side-chain cleavage enzyme, mitochondrial |
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| Ligand | BDBM50600667 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_2234669 (CHEMBL5148441) |
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| IC50 | 2700±n/a nM |
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| Citation |  Wu, T; Salim, AA; Khalil, ZG; Bernhardt, PV; Capon, RJ Glenthmycins A-M: Macrocyclic Spirotetronate Polyketide Antibacterials from the Australian Pasture Plant-Derived J Nat Prod85:1641-1657 (2022) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Cholesterol side-chain cleavage enzyme, mitochondrial |
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| Name: | Cholesterol side-chain cleavage enzyme, mitochondrial |
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| Synonyms: | CP11A_RAT | Cyp11a | Cyp11a-1 | Cyp11a1 | Cytochrome P450 11A1 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 60603.33 |
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| Organism: | Rattus norvegicus |
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| Description: | ChEMBL_50353 |
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| Residue: | 526 |
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| Sequence: | MLAKGLCLRSVLVKSCQPFLSPVWQGPGLATGNGAGISSTNSPRSFNEIPSPGDNGWINL
YHFLRENGTHRIHYHHMQNFQKYGPIYREKLGNMESVYILDPKDAATLFSCEGPNPERYL
VPPWVAYHQYYQRPIGVLFKSSDAWRKDRIVLNQEVMAPDSIKNFVPLLEGVAQDFIKVL
HRRIKQQNSGKFSGDISDDLFRFAFESITSVVFGERLGMLEEIVDPESQRFIDAVYQMFH
TSVPMLNMPPDLFRLFRTKTWKDHAAAWDVIFSKADEYTQNFYWDLRQKRDFSKYPGVLY
SLLGGNKLPFKNIQANITEMLAGGVDTTSMTLQWNLYEMAHNLKVQEMLRAEVLAARRQA
QGDMAKMVQLVPLLKASIKETLRLHPISVTLQRYIVNDLVLRNYKIPAKTLVQVASYAMG
RESSFFPNPNKFDPTRWLEKSQNTTHFRYLGFGWGVRQCLGRRIAELEMTIFLINVLENF
RIEVQSIRDVGTKFNLILMPEKPIFFNFQPLKQDLGSTMPRKGDTV
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| BDBM50600667 |
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| n/a |
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| Name | BDBM50600667 |
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| Synonyms: | CHEMBL5180164 |
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| Type | Small organic molecule |
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| Emp. Form. | C48H60O14 |
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| Mol. Mass. | 860.9816 |
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| SMILES | [H][C@]12C=C(C)[C@@]3([H])\C(C)=C\CC\C(C)=C\[C@]4([H])C=C([C@H](C)C[C@]44OC(=O)C(=C4O)C(=O)[C@@]3(C)[C@]1([H])[C@@H](C)CC[C@@H]2O[C@@H]1O[C@H](C)[C@@H](O)[C@@H](O)[C@H]1OC(=O)c1c(C)cc(OC)cc1O)C(O)=O |r,c:17,27,t:2,8,13| |
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| Structure | 
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