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| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | Cannabinoid receptor 1 | ||
| Ligand | BDBM50600943 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | ChEMBL_2235434 (CHEMBL5149206) | ||
| Ki | 5000±n/a nM | ||
| Citation |  Gündel, D; Deuther-Conrad, W; Ueberham, L; Kaur, S; Otikova, E; Teodoro, R; Toussaint, M; Lai, TH; Clauß, O; Scheunemann, M; Bormans, G; Bachmann, M; Kopka, K; Brust, P; Moldovan, RP Structure-Based Design, Optimization, and Development of [ J Med Chem65:9034-9049 (2022) [PubMed] Article | ||
| More Info.: | Get all data from this article, Assay Method | ||
| Cannabinoid receptor 1 | |||
| Name: | Cannabinoid receptor 1 | ||
| Synonyms: | CANN6 | CANNABINOID CB1 | CB-R | CB1 | CNR | CNR1 | CNR1_HUMAN | Cannabinoid CB1 receptor | Cannabinoid receptor | Cannabinoid receptor 1 (CB1) | Cannabinoid receptor 1 (brain) | ||
| Type: | G Protein-Coupled Receptor (GPCR) | ||
| Mol. Mass.: | 52868.96 | ||
| Organism: | Homo sapiens (Human) | ||
| Description: | P21554 | ||
| Residue: | 472 | ||
| Sequence: |
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| BDBM50600943 | |||
| n/a | |||
| Name | BDBM50600943 | ||
| Synonyms: | CHEMBL5170143 | ||
| Type | Small organic molecule | ||
| Emp. Form. | C27H26FN3O3 | ||
| Mol. Mass. | 459.512 | ||
| SMILES | C[C@H]1CC[C@@H](CC1)NC(=O)c1cc2cc(cnc2n(Cc2cccc(F)c2)c1=O)-c1ccco1 |r,wU:1.0,wD:4.7,(8.58,5,;7.24,4.23,;7.24,2.69,;5.91,1.92,;4.57,2.69,;4.57,4.23,;5.91,5,;3.24,1.92,;1.91,2.69,;1.91,4.23,;.58,1.92,;-.76,2.69,;-2.09,1.93,;-3.42,2.7,;-4.75,1.93,;-4.75,.38,;-3.42,-.38,;-2.09,.39,;-.75,-.39,;-.75,-1.93,;.58,-2.7,;.58,-4.24,;1.92,-5,;3.25,-4.24,;3.25,-2.69,;4.58,-1.92,;1.92,-1.93,;.58,.39,;1.91,-.38,;-6.09,2.7,;-6.42,4.19,;-7.96,4.36,;-8.58,2.99,;-7.42,1.93,)| | ||
| Structure | 
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