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| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | Cannabinoid receptor 2 | ||
| Ligand | BDBM50600946 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | ChEMBL_2235435 (CHEMBL5149207) | ||
| Ki | >10000±n/a nM | ||
| Citation |  Gündel, D; Deuther-Conrad, W; Ueberham, L; Kaur, S; Otikova, E; Teodoro, R; Toussaint, M; Lai, TH; Clauß, O; Scheunemann, M; Bormans, G; Bachmann, M; Kopka, K; Brust, P; Moldovan, RP Structure-Based Design, Optimization, and Development of [ J Med Chem65:9034-9049 (2022) [PubMed] Article | ||
| More Info.: | Get all data from this article, Assay Method | ||
| Cannabinoid receptor 2 | |||
| Name: | Cannabinoid receptor 2 | ||
| Synonyms: | CANNABINOID CB2 | CB-2 | CB2 | CB2A | CB2B | CNR2 | CNR2_HUMAN | CX5 | Cannabinoid CB2 receptor | Cannabinoid receptor 2 (CB2) | Cannabinoid receptor 2 (CB2R) | hCB2 | ||
| Type: | G Protein-Coupled Receptor (GPCR) | ||
| Mol. Mass.: | 39690.94 | ||
| Organism: | Homo sapiens (Human) | ||
| Description: | P34972 | ||
| Residue: | 360 | ||
| Sequence: |
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| BDBM50600946 | |||
| n/a | |||
| Name | BDBM50600946 | ||
| Synonyms: | CHEMBL5185306 | ||
| Type | Small organic molecule | ||
| Emp. Form. | C23H26FN3O3 | ||
| Mol. Mass. | 411.4692 | ||
| SMILES | C[C@H]1CC[C@H](CC1)NC(=O)c1cc2cc(cnc2n(CCCF)c1=O)-c1ccco1 |r,wD:4.7,1.0,(8.58,5,;7.24,4.23,;5.91,5,;4.57,4.23,;4.57,2.69,;5.91,1.92,;7.24,2.69,;3.24,1.92,;1.91,2.69,;1.91,4.23,;.57,1.92,;-.76,2.69,;-2.09,1.93,;-3.42,2.7,;-4.75,1.93,;-4.75,.38,;-3.42,-.38,;-2.09,.39,;-.75,-.38,;-.75,-1.92,;-2.09,-2.69,;-2.09,-4.23,;-3.42,-5,;.58,.39,;1.91,-.38,;-6.09,2.7,;-6.42,4.19,;-7.96,4.36,;-8.58,2.99,;-7.42,1.93,)| | ||
| Structure | 
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