| Reaction Details |
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 | Report a problem with these data |
| Target | Apoptosis regulator Bcl-2 |
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| Ligand | BDBM50601447 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_2236998 (CHEMBL5150894) |
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| IC50 | 460±n/a nM |
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| Citation |  Dhokne, P; Sakla, AP; Shankaraiah, N Structural insights of oxindole based kinase inhibitors as anticancer agents: Recent advances. Eur J Med Chem216:0 (2021) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Apoptosis regulator Bcl-2 |
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| Name: | Apoptosis regulator Bcl-2 |
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| Synonyms: | Apoptosis regulator Bcl-2 Protein | B-cell lymphoma 2 protein (Bcl-2) | BCL-2 | BCL2 | BCL2_HUMAN | Bcl-2 Protein |
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| Type: | Homodimer or heterodimer |
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| Mol. Mass.: | 26269.11 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P10415 |
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| Residue: | 239 |
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| Sequence: | MAHAGRTGYDNREIVMKYIHYKLSQRGYEWDAGDVGAAPPGAAPAPGIFSSQPGHTPHPA
ASRDPVARTSPLQTPAAPGAAAGPALSPVPPVVHLTLRQAGDDFSRRYRRDFAEMSSQLH
LTPFTARGRFATVVEELFRDGVNWGRIVAFFEFGGVMCVESVNREMSPLVDNIALWMTEY
LNRHLHTWIQDNGGWDAFVELYGPSMRPLFDFSWLSLKTLLSLALVGACITLGAYLGHK
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| BDBM50601447 |
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| n/a |
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| Name | BDBM50601447 |
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| Synonyms: | CHEMBL5196783 |
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| Type | Small organic molecule |
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| Emp. Form. | C21H20N4O |
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| Mol. Mass. | 344.4097 |
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| SMILES | CCCn1cc(\C=N\N=C2/C(=O)Nc3ccc(C)cc23)c2ccccc12 |
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| Structure | 
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