| Reaction Details |
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 | Report a problem with these data |
| Target | Sigma intracellular receptor 2 |
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| Ligand | BDBM50603207 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_2243444 (CHEMBL5157654) |
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| Ki | 171±n/a nM |
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| Citation |  Jonas, H; Aiello, D; Schepmann, D; Diana, P; Wünsch, B Synthesis of 8-aminomorphans with high KOR affinity. Eur J Med Chem230:0 (2022) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Sigma intracellular receptor 2 |
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| Name: | Sigma intracellular receptor 2 |
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| Synonyms: | S2r | SGMR2_RAT | Sigma intracellular receptor 2 | Sigma-2 receptor | Sigma2 receptor | Tmem97 | Transmembrane protein 97 |
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| Type: | Protein |
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| Mol. Mass.: | 20953.88 |
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| Organism: | Rattus norvegicus (Rat) |
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| Description: | Q5U3Y7 |
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| Residue: | 176 |
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| Sequence: | MGAVTARRCVEWLLGLYFVSHIPITMFIDLQALLPPELYPQEFSNLLRWYSKEFKDPLMQ
EPPVWFKSFLFCELVFQLPFFPIAAYAFFKGSCRWIRIPAIIYAVHTITTLIPILYTILF
EDFSKAIAFKGQRPENFRERLTLVGVYAPYLIIPLILLLFMLRNPYYKFEEKRKKK
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| BDBM50603207 |
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| n/a |
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| Name | BDBM50603207 |
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| Synonyms: | CHEMBL5185196 |
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| Type | Small organic molecule |
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| Emp. Form. | C19H24Cl2N2O |
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| Mol. Mass. | 367.313 |
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| SMILES | [H][C@@]12C[C@H](N3CCCC3)[C@@]([H])(C1)N(CC2)C(=O)Cc1ccc(Cl)c(Cl)c1 |r,THB:4:3:12.13.14:11,15:12:11:3.2| |
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| Structure | 
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