| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Sigma intracellular receptor 2 |
|---|
| Ligand | BDBM50603210 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_2243444 (CHEMBL5157654) |
|---|
| Ki | 154±n/a nM |
|---|
| Citation |  Jonas, H; Aiello, D; Schepmann, D; Diana, P; Wünsch, B Synthesis of 8-aminomorphans with high KOR affinity. Eur J Med Chem230:0 (2022) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Sigma intracellular receptor 2 |
|---|
| Name: | Sigma intracellular receptor 2 |
|---|
| Synonyms: | S2r | SGMR2_RAT | Sigma intracellular receptor 2 | Sigma-2 receptor | Sigma2 receptor | Tmem97 | Transmembrane protein 97 |
|---|
| Type: | Protein |
|---|
| Mol. Mass.: | 20953.88 |
|---|
| Organism: | Rattus norvegicus (Rat) |
|---|
| Description: | Q5U3Y7 |
|---|
| Residue: | 176 |
|---|
| Sequence: | MGAVTARRCVEWLLGLYFVSHIPITMFIDLQALLPPELYPQEFSNLLRWYSKEFKDPLMQ
EPPVWFKSFLFCELVFQLPFFPIAAYAFFKGSCRWIRIPAIIYAVHTITTLIPILYTILF
EDFSKAIAFKGQRPENFRERLTLVGVYAPYLIIPLILLLFMLRNPYYKFEEKRKKK
|
|
|
|---|
| BDBM50603210 |
|---|
| n/a |
|---|
| Name | BDBM50603210 |
|---|
| Synonyms: | CHEMBL5203422 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C20H26Cl2N2O |
|---|
| Mol. Mass. | 381.339 |
|---|
| SMILES | [H][C@]12CC[C@@H](N3CCCC3)[C@]([H])(C1)N(CC2)C(=O)Cc1ccc(Cl)c(Cl)c1 |r,THB:16:13:4.3.2:12,5:4:12:13.15.14| |
|---|
| Structure | 
|
|---|
Search and Browse
