| Reaction Details |
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 | Report a problem with these data |
| Target | Peroxisome proliferator-activated receptor delta |
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| Ligand | BDBM50184664 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_355606 (CHEMBL853178) |
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| EC50 | 70±n/a nM |
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| Citation |  Epple, R; Azimioara, M; Russo, R; Bursulaya, B; Tian, SS; Gerken, A; Iskandar, M 1,3,5-Trisubstituted aryls as highly selective PPARdelta agonists. Bioorg Med Chem Lett16:2969-73 (2006) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Peroxisome proliferator-activated receptor delta |
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| Name: | Peroxisome proliferator-activated receptor delta |
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| Synonyms: | NR1C2 | NUC1 | NUCI | Nuclear hormone receptor 1 | Nuclear receptor subfamily 1 group C member 2 | PPAR delta | PPAR-beta | PPARB | PPARD | PPARD_HUMAN | Peroxisome proliferator-activated receptor | Peroxisome proliferator-activated receptor beta | Peroxisome proliferator-activated receptor delta |
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| Type: | Enzyme |
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| Mol. Mass.: | 49910.45 |
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| Organism: | Homo sapiens (Human) |
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| Description: | Q03181 |
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| Residue: | 441 |
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| Sequence: | MEQPQEEAPEVREEEEKEEVAEAEGAPELNGGPQHALPSSSYTDLSRSSSPPSLLDQLQM
GCDGASCGSLNMECRVCGDKASGFHYGVHACEGCKGFFRRTIRMKLEYEKCERSCKIQKK
NRNKCQYCRFQKCLALGMSHNAIRFGRMPEAEKRKLVAGLTANEGSQYNPQVADLKAFSK
HIYNAYLKNFNMTKKKARSILTGKASHTAPFVIHDIETLWQAEKGLVWKQLVNGLPPYKE
ISVHVFYRCQCTTVETVRELTEFAKSIPSFSSLFLNDQVTLLKYGVHEAIFAMLASIVNK
DGLLVANGSGFVTREFLRSLRKPFSDIIEPKFEFAVKFNALELDDSDLALFIAAIILCGD
RPGLMNVPRVEAIQDTILRALEFHLQANHPDAQYLFPKLLQKMADLRQLVTEHAQMMQRI
KKTETETSLHPLLQEIYKDMY
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| BDBM50184664 |
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| n/a |
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| Name | BDBM50184664 |
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| Synonyms: | CHEMBL425945 | [2-methyl-4-(4-methyl-4''-trifluoromethyl-[1,1';3',1'']terphenyl-5'-ylmethoxy)-phenoxy]-acetic acid |
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| Type | Small organic molecule |
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| Emp. Form. | C30H25F3O4 |
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| Mol. Mass. | 506.5123 |
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| SMILES | Cc1ccc(cc1)-c1cc(COc2ccc(OCC(O)=O)c(C)c2)cc(c1)-c1ccc(cc1)C(F)(F)F |
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| Structure | 
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