| Reaction Details |
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 | Report a problem with these data |
| Target | Dipeptidyl peptidase 1 |
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| Ligand | BDBM50186091 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_375063 (CHEMBL864709) |
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| IC50 | 172±n/a nM |
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| Citation |  Bondebjerg, J; Fuglsang, H; Valeur, KR; Pedersen, J; Naerum, L Dipeptidyl nitriles as human dipeptidyl peptidase I inhibitors. Bioorg Med Chem Lett16:3614-7 (2006) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Dipeptidyl peptidase 1 |
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| Name: | Dipeptidyl peptidase 1 |
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| Synonyms: | CATC_HUMAN | CPPI | CTSC | Cathepsin C | Cathepsin J | Dipeptidyl peptidase 1 (DDPI) | Dipeptidyl peptidase 1 (DPPI) | Dipeptidyl peptidase I | Dipeptidyl peptidase I (DPPI) |
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| Type: | Enzyme |
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| Mol. Mass.: | 51857.28 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P53634 |
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| Residue: | 463 |
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| Sequence: | MGAGPSLLLAALLLLLSGDGAVRCDTPANCTYLDLLGTWVFQVGSSGSQRDVNCSVMGPQ
EKKVVVYLQKLDTAYDDLGNSGHFTIIYNQGFEIVLNDYKWFAFFKYKEEGSKVTTYCNE
TMTGWVHDVLGRNWACFTGKKVGTASENVYVNIAHLKNSQEKYSNRLYKYDHNFVKAINA
IQKSWTATTYMEYETLTLGDMIRRSGGHSRKIPRPKPAPLTAEIQQKILHLPTSWDWRNV
HGINFVSPVRNQASCGSCYSFASMGMLEARIRILTNNSQTPILSPQEVVSCSQYAQGCEG
GFPYLIAGKYAQDFGLVEEACFPYTGTDSPCKMKEDCFRYYSSEYHYVGGFYGGCNEALM
KLELVHHGPMAVAFEVYDDFLHYKKGIYHHTGLRDPFNPFELTNHAVLLVGYGTDSASGM
DYWIVKNSWGTGWGENGYFRIRRGTDECAIESIAVAATPIPKL
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| BDBM50186091 |
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| n/a |
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| Name | BDBM50186091 |
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| Synonyms: | (S)-2-amino-N-((S)-1-cyano-2-phenylethyl)butanamide | CHEMBL439145 |
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| Type | Small organic molecule |
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| Emp. Form. | C13H17N3O |
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| Mol. Mass. | 231.2936 |
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| SMILES | CC[C@H](N)C(=O)N[C@@H](Cc1ccccc1)C#N |
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| Structure | 
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