| Reaction Details |
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 | Report a problem with these data |
| Target | Group IIE secretory phospholipase A2 |
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| Ligand | BDBM50055366 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_352636 (CHEMBL862127) |
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| IC50 | 50±n/a nM |
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| Citation |  Smart, BP; Oslund, RC; Walsh, LA; Gelb, MH The first potent inhibitor of mammalian group X secreted phospholipase A2: elucidation of sites for enhanced binding. J Med Chem49:2858-60 (2006) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Group IIE secretory phospholipase A2 |
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| Name: | Group IIE secretory phospholipase A2 |
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| Synonyms: | GIIE sPLA2 | PA2GE_HUMAN | PLA2G2E | Phosphatidylcholine 2-acylhydrolase GIIE | sPLA(2)-IIE |
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| Type: | PROTEIN |
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| Mol. Mass.: | 15997.10 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_489274 |
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| Residue: | 142 |
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| Sequence: | MKSPHVLVFLCLLVALVTGNLVQFGVMIEKMTGKSALQYNDYGCYCGIGGSHWPVDQTDW
CCHAHDCCYGRLEKLGCEPKLEKYLFSVSERGIFCAGRTTCQRLTCECDKRAALCFRRNL
GTYNRKYAHYPNKLCTGPTPPC
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| BDBM50055366 |
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| n/a |
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| Name | BDBM50055366 |
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| Synonyms: | (3-Aminooxalyl-1-benzyl-2-ethyl-1H-indol-4-yloxy)-acetic acid | (3-Aminooxalyl-1-benzyl-2-ethyl-2,3-dihydro-1H-indol-4-yloxy)-acetic acid | 2-(3-(2-amino-2-oxoacetyl)-1-benzyl-2-ethyl-1H-indol-4-yloxy)acetic acid | CHEMBL148674 | Varespladib sodium |
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| Type | Small organic molecule |
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| Emp. Form. | C21H20N2O5 |
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| Mol. Mass. | 380.3939 |
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| SMILES | CCc1c(C(=O)C(N)=O)c2c(OCC(O)=O)cccc2n1Cc1ccccc1 |
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| Structure | 
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