| Reaction Details |
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 | Report a problem with these data |
| Target | Monocarboxylate transporter 1 |
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| Ligand | BDBM50606662 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_2261030 (CHEMBL5216041) |
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| Ki | 2.3±n/a nM |
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| Citation |  Wang, Y; Qin, L; Chen, W; Chen, Q; Sun, J; Wang, G Novel strategies to improve tumour therapy by targeting the proteins MCT1, MCT4 and LAT1. Eur J Med Chem226:0 (2021) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Monocarboxylate transporter 1 |
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| Name: | Monocarboxylate transporter 1 |
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| Synonyms: | MCT 1 | MOT1_RAT | Mct1 | Monocarboxylate transporter 1 | Monocarboxylate transporter 1 (MCT1) | Slc16a1 | Solute carrier family 16 member 1 |
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| Type: | Enzyme |
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| Mol. Mass.: | 53245.17 |
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| Organism: | Rattus norvegicus (Rat) |
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| Description: | P53987 |
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| Residue: | 494 |
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| Sequence: | MPPAIGGPVGYTPPDGGWGWAVVVGAFISIGFSYAFPKSITVFFKEIEIIFSATTSEVSW
ISSIMLAVMYAGGPISSILVNKYGSRPVMIAGGCLSGCGLIAASFCNTVQELYFCIGVIG
GLGLAFNLNPALTMIGKYFYKKRPLANGLAMAGSPVFLSTLAPLNQAFFGIFGWRGSFLI
LGGLLLNCCVAGSLMRPIGPQQGKVEKLKSKESLQEAGKSDANTDLIGGSPKGEKLSVFQ
TVNKFLDLSLFTHRGFLLYLSGNVVMFFGLFTPLVFLSNYGKSKHFSSEKSAFLLSILAF
VDMVARPSMGLAANTRWIRPRVQYFFAASVVANGVCHLLAPLSTTYVGFCIYAGVFGFAF
GWLSSVLFETLMDLVGPQRFSSAVGLVTIVECCPVLLGPPLLGRLNDMYGDYKYTYWACG
VILIIAGLYLFIGMGINYRLVAKEQKAEEKKRDGKEDETSTDVDEKPKKTMKETQSPAPL
QNSSGDPAEEESPV
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| BDBM50606662 |
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| n/a |
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| Name | BDBM50606662 |
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| Synonyms: | CHEMBL5221129 |
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| Type | Small organic molecule |
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| Emp. Form. | C21H27N5O5S |
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| Mol. Mass. | 461.535 |
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| SMILES | CC(C)Cn1c2sc(Cc3c(C)n[nH]c3C)c(C(=O)N3C[C@@H](O)CO3)c2c(=O)n(C)c1=O |r| |
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| Structure | 
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