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| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | Cyclin-dependent kinase 9 | ||
| Ligand | BDBM50553499 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | ChEMBL_2264678 | ||
| IC50 | 4.0±n/a nM | ||
| Citation |  Huang, Z; Wang, T; Wang, C; Fan, Y CDK9 inhibitors in cancer research. RSC Med Chem13:688-710 (2022) [PubMed] | ||
| More Info.: | Get all data from this article, Assay Method | ||
| Cyclin-dependent kinase 9 | |||
| Name: | Cyclin-dependent kinase 9 | ||
| Synonyms: | C-2K | CDC2L4 | CDK9 | CDK9_HUMAN | Cell division cycle 2-like protein kinase 4 | Cell division protein kinase 9 | Cyclin-Dependent Kinase 9 (CDK9) | Cyclin-dependent kinase 9 (CDK9) | Serine/threonine-protein kinase PITALRE | TAK | Tat-associated kinase complex catalytic subunit | ||
| Type: | Enzyme Subunit | ||
| Mol. Mass.: | 42789.13 | ||
| Organism: | Homo sapiens (Human) | ||
| Description: | n/a | ||
| Residue: | 372 | ||
| Sequence: |
| ||
| BDBM50553499 | |||
| n/a | |||
| Name | BDBM50553499 | ||
| Synonyms: | CHEMBL4754493 | ||
| Type | Small organic molecule | ||
| Emp. Form. | C18H25ClN6 | ||
| Mol. Mass. | 360.884 | ||
| SMILES | Cn1ncc(c1CC1CC1)-c1nc(N[C@H]2CC[C@H](N)CC2)ncc1Cl |r,wU:14.15,wD:17.19,(8.24,3.69,;6.99,4.59,;6.99,6.13,;5.53,6.61,;4.62,5.36,;5.53,4.12,;5.05,2.65,;6.08,1.51,;7.54,1.03,;6.4,,;3.08,5.36,;2.31,6.69,;.77,6.69,;,8.03,;.77,9.36,;,10.7,;.77,12.03,;2.31,12.03,;3.08,13.36,;3.08,10.7,;2.31,9.36,;,5.36,;.77,4.03,;2.31,4.03,;3.08,2.69,)| | ||
| Structure | 
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