Reaction Details |
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Target | G-protein coupled receptor 55 |
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Ligand | BDBM50405853 |
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Substrate/Competitor | n/a |
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Meas. Tech. | ChEMBL_2265979 |
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IC50 | 280±n/a nM |
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Citation | Figuerola-Asencio, L; Morales, P; Zhao, P; Hurst, DP; Sayed, SS; Colón, KL; Gómez-Cañas, M; Fernández-Ruiz, J; Croatt, MP; Reggio, PH; Abood, ME; Jagerovic, N Thienopyrimidine Derivatives as GPR55 Receptor Antagonists: Insight into Structure-Activity Relationship. ACS Med Chem Lett14:18-25 (2023) [PubMed] |
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More Info.: | Get all data from this article, Assay Method |
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G-protein coupled receptor 55 |
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Name: | G-protein coupled receptor 55 |
Synonyms: | G protein-coupled receptor 55 | GPR55 | GPR55_HUMAN |
Type: | PROTEIN |
Mol. Mass.: | 36649.72 |
Organism: | Homo sapiens (Human) |
Description: | ChEMBL_1292265 |
Residue: | 319 |
Sequence: | MSQQNTSGDCLFDGVNELMKTLQFAVHIPTFVLGLLLNLLAIHGFSTFLKNRWPDYAATS
IYMINLAVFDLLLVLSLPFKMVLSQVQSPFPSLCTLVECLYFVSMYGSVFTICFISMDRF
LAIRYPLLVSHLRSPRKIFGICCTIWVLVWTGSIPIYSFHGKVEKYMCFHNMSDDTWSAK
VFFPLEVFGFLLPMGIMGFCCSRSIHILLGRRDHTQDWVQQKACIYSIAASLAVFVVSFL
PVHLGFFLQFLVRNSFIVECRAKQSISFFLQLSMCFSNVNCCLDVFCYYFVIKEFRMNIR
AHRPSRVQLVLQDTTISRG
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BDBM50405853 |
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n/a |
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Name | BDBM50405853 |
Synonyms: | CHEMBL5273189 |
Type | Small organic molecule |
Emp. Form. | C22H26N4O2S |
Mol. Mass. | 410.532 |
SMILES | Cc1nc(N2CCN(CC2)C(=O)c2ccco2)c2c3CCC(C)(C)Cc3sc2n1 |
Structure |
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