| Reaction Details |
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 | Report a problem with these data |
| Target | G-protein coupled receptor 55 |
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| Ligand | BDBM50405859 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_2265979 |
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| IC50 | 3000±n/a nM |
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| Citation |  Figuerola-Asencio, L; Morales, P; Zhao, P; Hurst, DP; Sayed, SS; Colón, KL; Gómez-Cañas, M; Fernández-Ruiz, J; Croatt, MP; Reggio, PH; Abood, ME; Jagerovic, N Thienopyrimidine Derivatives as GPR55 Receptor Antagonists: Insight into Structure-Activity Relationship. ACS Med Chem Lett14:18-25 (2023) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| G-protein coupled receptor 55 |
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| Name: | G-protein coupled receptor 55 |
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| Synonyms: | G protein-coupled receptor 55 | GPR55 | GPR55_HUMAN |
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| Type: | PROTEIN |
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| Mol. Mass.: | 36649.72 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_1292265 |
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| Residue: | 319 |
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| Sequence: | MSQQNTSGDCLFDGVNELMKTLQFAVHIPTFVLGLLLNLLAIHGFSTFLKNRWPDYAATS
IYMINLAVFDLLLVLSLPFKMVLSQVQSPFPSLCTLVECLYFVSMYGSVFTICFISMDRF
LAIRYPLLVSHLRSPRKIFGICCTIWVLVWTGSIPIYSFHGKVEKYMCFHNMSDDTWSAK
VFFPLEVFGFLLPMGIMGFCCSRSIHILLGRRDHTQDWVQQKACIYSIAASLAVFVVSFL
PVHLGFFLQFLVRNSFIVECRAKQSISFFLQLSMCFSNVNCCLDVFCYYFVIKEFRMNIR
AHRPSRVQLVLQDTTISRG
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| BDBM50405859 |
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| n/a |
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| Name | BDBM50405859 |
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| Synonyms: | CHEMBL5271818 |
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| Type | Small organic molecule |
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| Emp. Form. | C20H18N4O2S |
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| Mol. Mass. | 378.448 |
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| SMILES | Cc1nc(N2CCN(CC2)C(=O)c2ccco2)c2c(n1)sc1ccccc21 |
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| Structure | 
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