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TargetNAD-dependent protein deacylase sirtuin-6
LigandBDBM22231
Substrate/Competitorn/a
Meas. Tech.ChEMBL_2268096
EC50 230000±n/a nM
Citation Fiorentino, FMai, ARotili, D Emerging Therapeutic Potential of SIRT6 Modulators. J Med Chem64:9732-9758 (2021) [PubMed]
More Info.:Get all data from this article,  Assay Method
 
NAD-dependent protein deacylase sirtuin-6
Name:NAD-dependent protein deacylase sirtuin-6
Synonyms:NAD-dependent protein deacetylase sirtuin-6 | NAD-dependent protein deacetylase sirtuin-6 (SIRT6) | Regulatory protein SIR2 homolog 6 | SIR2-like protein 6 | SIR2L6 | SIR6_HUMAN | SIRT6 | Sirtuin-6 (SIRT6)
Type:Protein
Mol. Mass.:39133.03
Organism:Homo sapiens (Human)
Description:Q8N6T7
Residue:355
Sequence:
MSVNYAAGLSPYADKGKCGLPEIFDPPEELERKVWELARLVWQSSSVVFHTGAGISTASG
IPDFRGPHGVWTMEERGLAPKFDTTFESARPTQTHMALVQLERVGLLRFLVSQNVDGLHV
RSGFPRDKLAELHGNMFVEECAKCKTQYVRDTVVGTMGLKATGRLCTVAKARGLRACRGE
LRDTILDWEDSLPDRDLALADEASRNADLSITLGTSLQIRPSGNLPLATKRRGGRLVIVN
LQPTKHDRHADLRIHGYVDEVMTRLMKHLGLEIPAWDGPRVLERALPPLPRPPTPKLEPK
EESPTRINGSIPAGPKQEPCAQHNGSEPASPKRERPTSPAPHRPPKRVKAKAVPS
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  Blast E-value cutoff:
BDBM22231
n/a
NameBDBM22231
Synonyms:(9Z,12Z)-octadeca-9,12-dienoic acid | CHEMBL267476 | Linoleic Acid | Linoleic acid (LA)
TypeUnsaturated fatty acid
Emp. Form.C18H32O2
Mol. Mass.280.4455
SMILESCCCCC\C=C/C\C=C/CCCCCCCC(O)=O
Structure
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