| Reaction Details |
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 | Report a problem with these data |
| Target | Cyclin-dependent kinase 5 |
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| Ligand | BDBM50378657 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_2270752 |
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| IC50 | 5.0±n/a nM |
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| Citation |  Marak, BN; Dowarah, J; Khiangte, L; Singh, VP A comprehensive insight on the recent development of Cyclic Dependent Kinase inhibitors as anticancer agents. Eur J Med Chem203:0 (2020) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Cyclin-dependent kinase 5 |
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| Name: | Cyclin-dependent kinase 5 |
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| Synonyms: | CDK5 | CDK5_HUMAN | CDKN5 | Cell division protein kinase 5 | Cyclin-dependent kinase 5 (CDK5/ p25) | Cyclin-dependent kinase 5 (CDK5/p35) | Cyclin-dependent-like kinase 5 | Cyclin-dependent-like kinase 5 (CDK5) | PSSALRE | Serine/threonine-protein kinase PSSALRE | Tau protein kinase II catalytic subunit |
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| Type: | Enzyme Subunit |
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| Mol. Mass.: | 33308.61 |
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| Organism: | Homo sapiens (Human) |
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| Description: | n/a |
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| Residue: | 292 |
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| Sequence: | MQKYEKLEKIGEGTYGTVFKAKNRETHEIVALKRVRLDDDDEGVPSSALREICLLKELKH
KNIVRLHDVLHSDKKLTLVFEFCDQDLKKYFDSCNGDLDPEIVKSFLFQLLKGLGFCHSR
NVLHRDLKPQNLLINRNGELKLADFGLARAFGIPVRCYSAEVVTLWYRPPDVLFGAKLYS
TSIDMWSAGCIFAELANAGRPLFPGNDVDDQLKRIFRLLGTPTEEQWPSMTKLPDYKPYP
MYPATTSLVNVVPKLNATGRDLLQNLLKCNPVQRISAEEALQHPYFSDFCPP
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| BDBM50378657 |
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| n/a |
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| Name | BDBM50378657 |
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| Synonyms: | CHEMBL1230607 |
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| Type | Small organic molecule |
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| Emp. Form. | C19H31N5O2 |
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| Mol. Mass. | 361.4817 |
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| SMILES | CC(C)CC(=O)Nc1[nH]nc2c1CN(C(=O)C1CCN(C)CC1)C2(C)C |
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| Structure | 
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