| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Urea transporter 1 |
|---|
| Ligand | BDBM50607930 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_2271892 |
|---|
| IC50 | 470000±n/a nM |
|---|
| Citation |  Titko, T; Perekhoda, L; Drapak, I; Tsapko, Y Modern trends in diuretics development. Eur J Med Chem208:0 (2020) [PubMed] |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Urea transporter 1 |
|---|
| Name: | Urea transporter 1 |
|---|
| Synonyms: | Slc14a1 | UT11 | UT1_RAT | UT3 | Urea transporter B (UT-B) |
|---|
| Type: | Protein |
|---|
| Mol. Mass.: | 42037.85 |
|---|
| Organism: | Rattus norvegicus (Rat) |
|---|
| Description: | n/a |
|---|
| Residue: | 384 |
|---|
| Sequence: | MEDIPTMVKVDRGESQILSCRGRRCGLKVLGYVTGDMKEFANWLKDKPVVLQFMDWILRG
ISQVVFVSNPISGILILAGLLVQNPWWALCGCVGTVVSTLTALLLSQDRSAIAAGLQGYN
ATLVGILMAVFSDKGDYFWWLIFPVSAMSMTCPVFSSALSSLFSKWDLPVFTLPFNMALS
LYLSATGHYNTFFPSKLFMPVSSVPNITWSELSALELLKSLPVGVGQIYGCDNPWTGAIF
LCAILLSSPLMCLHAAIGSLLGVIAGLSLAAPFKDIYSGLWGFNSSLACIAIGGMFMALT
WQTHLLALACALFTAYFGACMTHLMAAVHLPACTWSFCLATLLFLLLTTENPNIYRMPLS
KVTYSEENRIFYLQNKKRVVDSPL
|
|
|
|---|
| BDBM50607930 |
|---|
| n/a |
|---|
| Name | BDBM50607930 |
|---|
| Synonyms: | CHEMBL5276686 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C14H15NO4S |
|---|
| Mol. Mass. | 293.338 |
|---|
| SMILES | CCOC(=O)c1cc2c(N)c(sc2cc1C)C(=O)OC |
|---|
| Structure | 
|
|---|
Search and Browse
