| Reaction Details |
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 | Report a problem with these data |
| Target | Urea transporter 1 |
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| Ligand | BDBM50607933 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_2271892 |
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| IC50 | 280±n/a nM |
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| Citation |  Titko, T; Perekhoda, L; Drapak, I; Tsapko, Y Modern trends in diuretics development. Eur J Med Chem208:0 (2020) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Urea transporter 1 |
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| Name: | Urea transporter 1 |
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| Synonyms: | Slc14a1 | UT11 | UT1_RAT | UT3 | Urea transporter B (UT-B) |
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| Type: | Protein |
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| Mol. Mass.: | 42037.85 |
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| Organism: | Rattus norvegicus (Rat) |
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| Description: | n/a |
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| Residue: | 384 |
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| Sequence: | MEDIPTMVKVDRGESQILSCRGRRCGLKVLGYVTGDMKEFANWLKDKPVVLQFMDWILRG
ISQVVFVSNPISGILILAGLLVQNPWWALCGCVGTVVSTLTALLLSQDRSAIAAGLQGYN
ATLVGILMAVFSDKGDYFWWLIFPVSAMSMTCPVFSSALSSLFSKWDLPVFTLPFNMALS
LYLSATGHYNTFFPSKLFMPVSSVPNITWSELSALELLKSLPVGVGQIYGCDNPWTGAIF
LCAILLSSPLMCLHAAIGSLLGVIAGLSLAAPFKDIYSGLWGFNSSLACIAIGGMFMALT
WQTHLLALACALFTAYFGACMTHLMAAVHLPACTWSFCLATLLFLLLTTENPNIYRMPLS
KVTYSEENRIFYLQNKKRVVDSPL
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| BDBM50607933 |
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| n/a |
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| Name | BDBM50607933 |
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| Synonyms: | CHEMBL5269927 |
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| Type | Small organic molecule |
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| Emp. Form. | C22H21N5O4S |
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| Mol. Mass. | 451.498 |
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| SMILES | Cn1c2nc(SCC(=O)Nc3cccc(O)c3)n(Cc3ccccc3)c2c(=O)n(C)c1=O |
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| Structure | 
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