| Reaction Details |
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 | Report a problem with these data |
| Target | Aquaporin-1 |
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| Ligand | BDBM50607938 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_2271914 |
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| IC50 | 20000±n/a nM |
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| Citation |  Titko, T; Perekhoda, L; Drapak, I; Tsapko, Y Modern trends in diuretics development. Eur J Med Chem208:0 (2020) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Aquaporin-1 |
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| Name: | Aquaporin-1 |
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| Synonyms: | AQP1 | AQP1_HUMAN | Aquaporin-1 (AQP1) | CHIP28 |
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| Type: | Protein |
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| Mol. Mass.: | 28528.18 |
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| Organism: | Homo sapiens (Human) |
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| Description: | n/a |
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| Residue: | 269 |
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| Sequence: | MASEFKKKLFWRAVVAEFLATTLFVFISIGSALGFKYPVGNNQTAVQDNVKVSLAFGLSI
ATLAQSVGHISGAHLNPAVTLGLLLSCQISIFRALMYIIAQCVGAIVATAILSGITSSLT
GNSLGRNDLADGVNSGQGLGIEIIGTLQLVLCVLATTDRRRRDLGGSAPLAIGLSVALGH
LLAIDYTGCGINPARSFGSAVITHNFSNHWIFWVGPFIGGALAVLIYDFILAPRSSDLTD
RVKVWTSGQVEEYDLDADDINSRVEMKPK
|
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|
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| BDBM50607938 |
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| n/a |
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| Name | BDBM50607938 |
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| Synonyms: | CHEMBL5280895 |
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| Type | Small organic molecule |
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| Emp. Form. | C22H24N4O4S |
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| Mol. Mass. | 440.515 |
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| SMILES | CCCCNc1cc(cc(c1Oc1ccccc1)S(N)(=O)=O)C(=O)Nc1ccncc1 |
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| Structure | 
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