| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Aquaporin-1 |
|---|
| Ligand | BDBM50607941 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_2271916 |
|---|
| EC50 | 3300±n/a nM |
|---|
| Citation |  Titko, T; Perekhoda, L; Drapak, I; Tsapko, Y Modern trends in diuretics development. Eur J Med Chem208:0 (2020) [PubMed] |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Aquaporin-1 |
|---|
| Name: | Aquaporin-1 |
|---|
| Synonyms: | AQP1 | AQP1_HUMAN | Aquaporin-1 (AQP1) | CHIP28 |
|---|
| Type: | Protein |
|---|
| Mol. Mass.: | 28528.18 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | n/a |
|---|
| Residue: | 269 |
|---|
| Sequence: | MASEFKKKLFWRAVVAEFLATTLFVFISIGSALGFKYPVGNNQTAVQDNVKVSLAFGLSI
ATLAQSVGHISGAHLNPAVTLGLLLSCQISIFRALMYIIAQCVGAIVATAILSGITSSLT
GNSLGRNDLADGVNSGQGLGIEIIGTLQLVLCVLATTDRRRRDLGGSAPLAIGLSVALGH
LLAIDYTGCGINPARSFGSAVITHNFSNHWIFWVGPFIGGALAVLIYDFILAPRSSDLTD
RVKVWTSGQVEEYDLDADDINSRVEMKPK
|
|
|
|---|
| BDBM50607941 |
|---|
| n/a |
|---|
| Name | BDBM50607941 |
|---|
| Synonyms: | CHEMBL5268096 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C20H19ClN2O5S |
|---|
| Mol. Mass. | 434.893 |
|---|
| SMILES | COC(=O)c1cc(c(Cl)cc1NCc1ccco1)S(=O)(=O)NCc1ccccc1 |
|---|
| Structure | 
|
|---|
Search and Browse
