| Reaction Details |
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 | Report a problem with these data |
| Target | Histone deacetylase 3 |
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| Ligand | BDBM207629 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_2274091 |
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| Ki | 5.0±n/a nM |
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| Citation |  Sarkar, R; Banerjee, S; Amin, SA; Adhikari, N; Jha, T Histone deacetylase 3 (HDAC3) inhibitors as anticancer agents: A review. Eur J Med Chem192:0 (2020) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Histone deacetylase 3 |
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| Name: | Histone deacetylase 3 |
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| Synonyms: | HD3 | HDAC3 | HDAC3_HUMAN | Histone deacetylase 3 (HDAC3) | Human HDAC3 | RPD3-2 | SMAP45 |
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| Type: | Enzyme |
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| Mol. Mass.: | 48829.55 |
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| Organism: | Homo sapiens (Human) |
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| Description: | O15379 |
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| Residue: | 428 |
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| Sequence: | MAKTVAYFYDPDVGNFHYGAGHPMKPHRLALTHSLVLHYGLYKKMIVFKPYQASQHDMCR
FHSEDYIDFLQRVSPTNMQGFTKSLNAFNVGDDCPVFPGLFEFCSRYTGASLQGATQLNN
KICDIAINWAGGLHHAKKFEASGFCYVNDIVIGILELLKYHPRVLYIDIDIHHGDGVQEA
FYLTDRVMTVSFHKYGNYFFPGTGDMYEVGAESGRYYCLNVPLRDGIDDQSYKHLFQPVI
NQVVDFYQPTCIVLQCGADSLGCDRLGCFNLSIRGHGECVEYVKSFNIPLLVLGGGGYTV
RNVARCWTYETSLLVEEAISEELPYSEYFEYFAPDFTLHPDVSTRIENQNSRQYLDQIRQ
TIFENLKMLNHAPSVQIHDVPADLLTYDRTDEADAEERGPEENYSRPEAPNEFYDGDHDN
DKESDVEI
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| BDBM207629 |
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| n/a |
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| Name | BDBM207629 |
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| Synonyms: | US9265734, R01 | US9796664, Compound R01 |
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| Type | Small organic molecule |
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| Emp. Form. | C20H25N3O2 |
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| Mol. Mass. | 339.4314 |
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| SMILES | Cc1ccc(cc1)C(=O)NCCCCCC(=O)Nc1ccccc1N |
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| Structure | 
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