| Reaction Details |
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 | Report a problem with these data |
| Target | Monocarboxylate transporter 4 |
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| Ligand | BDBM214697 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_2274355 |
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| IC50 | 32±n/a nM |
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| Citation |  Puri, S; Juvale, K Monocarboxylate transporter 1 and 4 inhibitors as potential therapeutics for treating solid tumours: A review with structure-activity relationship insights. Eur J Med Chem199:0 (2020) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Monocarboxylate transporter 4 |
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| Name: | Monocarboxylate transporter 4 |
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| Synonyms: | MCT 4 | MCT3 | MCT4 | MOT4_HUMAN | SLC16A3 | Solute carrier family 16 member 3 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 49474.36 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_104604 |
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| Residue: | 465 |
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| Sequence: | MGGAVVDEGPTGVKAPDGGWGWAVLFGCFVITGFSYAFPKAVSVFFKELIQEFGIGYSDT
AWISSILLAMLYGTGPLCSVCVNRFGCRPVMLVGGLFASLGMVAASFCRSIIQVYLTTGV
ITGLGLALNFQPSLIMLNRYFSKRRPMANGLAAAGSPVFLCALSPLGQLLQDRYGWRGGF
LILGGLLLNCCVCAALMRPLVVTAQPGSGPPRPSRRLLDLSVFRDRGFVLYAVAASVMVL
GLFVPPVFVVSYAKDLGVPDTKAAFLLTILGFIDIFARPAAGFVAGLGKVRPYSVYLFSF
SMFFNGLADLAGSTAGDYGGLVVFCIFFGISYGMVGALQFEVLMAIVGTHKFSSAIGLVL
LMEAVAVLVGPPSGGKLLDATHVYMYVFILAGAEVLTSSLILLLGNFFCIRKKPKEPQPE
VAAAEEEKLHKPPADSGVDLREVEHFLKAEPEKNGEVVHTPETSV
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| BDBM214697 |
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| n/a |
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| Name | BDBM214697 |
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| Synonyms: | US9296728, 19 |
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| Type | Small organic molecule |
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| Emp. Form. | C25H22N2O3 |
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| Mol. Mass. | 398.4538 |
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| SMILES | COc1cc(ccc1\C=C(/C#N)C(O)=O)N(Cc1ccccc1)Cc1ccccc1 |
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| Structure | 
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