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TargetNeuropeptide Y receptor type 5
LigandBDBM50197013
Substrate/Competitorn/a
Meas. Tech.ChEMBL_453179 (CHEMBL902329)
Ki>1000±n/a nM
Citation DeCarr, LB; Buckholz, TM; Coish, PD; Fathi, Z; Fisk, SE; Mays, MR; O'Connor, SJ; Lumb, KJ Identification of selective neuropeptide Y2 peptide agonists. Bioorg Med Chem Lett17:538-41 (2007) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Neuropeptide Y receptor type 5
Name:Neuropeptide Y receptor type 5
Synonyms:NPY-Y5 | NPY-Y5 receptor | NPY5-R | NPY5R | NPY5R_HUMAN | NPYR5 | NPYY5 | Neuropeptide Y receptor type 5 | Neuropeptide Y receptor type 5 ( NPY Y5) | Y5 receptor
Type:Enzyme
Mol. Mass.:50746.64
Organism:Homo sapiens (Human)
Description:Q15761
Residue:445
Sequence:
MDLELDEYYNKTLATENNTAATRNSDFPVWDDYKSSVDDLQYFLIGLYTFVSLLGFMGNL
LILMALMKKRNQKTTVNFLIGNLAFSDILVVLFCSPFTLTSVLLDQWMFGKVMCHIMPFL
QCVSVLVSTLILISIAIVRYHMIKHPISNNLTANHGYFLIATVWTLGFAICSPLPVFHSL
VELQETFGSALLSSRYLCVESWPSDSYRIAFTISLLLVQYILPLVCLTVSHTSVCRSISC
GLSNKENRLEENEMINLTLHPSKKSGPQVKLSGSHKWSYSFIKKHRRRYSKKTACVLPAP
ERPSQENHSRILPENFGSVRSQLSSSSKFIPGVPTCFEIKPEENSDVHELRVKRSVTRIK
KRSRSVFYRLTILILVFAVSWMPLHLFHVVTDFNDNLISNRHFKLVYCICHLLGMMSCCL
NPILYGFLNNGIKADLVSLIHCLHM
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM50197013
n/a
NameBDBM50197013
Synonyms:AcPYY(25-36) | CHEMBL392889
TypeSmall organic molecule
Emp. Form.C74H118N26O18
Mol. Mass.1659.8921
SMILESCC(C)C[C@H](NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)[C@H](CCCN=C(N)N)NC(C)=O)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CCCN=C(N)N)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCCN=C(N)N)C(=O)N[C@@H](Cc1ccc(O)cc1)C(N)=O |wU:68.69,69.72,4.4,86.87,20.28,53.54,106.107,wD:61.62,8.17,30.39,75.76,45.46,95.96,(7.95,-35.96,;7.95,-37.5,;9.29,-38.27,;6.63,-38.27,;6.63,-39.81,;5.28,-40.57,;3.95,-39.8,;3.95,-38.26,;2.62,-40.57,;2.62,-42.11,;3.95,-42.88,;5.29,-42.11,;6.62,-42.88,;6.62,-44.42,;7.94,-45.18,;5.29,-45.19,;3.95,-44.42,;1.29,-39.8,;-.04,-40.59,;-.04,-42.13,;-1.37,-39.82,;-1.37,-38.28,;-.04,-37.51,;1.37,-38.14,;2.4,-36.99,;1.63,-35.66,;.12,-35.97,;-2.71,-40.58,;-4.04,-39.81,;-4.04,-38.27,;-5.37,-40.58,;-5.37,-42.12,;-4.04,-42.89,;-4.04,-44.43,;-2.71,-45.2,;-2.7,-46.74,;-4.05,-47.5,;-1.38,-47.5,;-6.71,-39.81,;-8.03,-40.6,;-9.36,-39.83,;-8.03,-42.14,;7.95,-40.58,;7.95,-42.12,;9.28,-39.8,;10.62,-40.57,;10.62,-42.11,;11.94,-42.88,;13.27,-42.11,;11.94,-44.42,;11.94,-39.8,;11.94,-38.26,;13.28,-40.57,;14.62,-39.81,;14.62,-38.27,;15.95,-37.5,;15.95,-35.96,;17.28,-38.27,;15.95,-40.58,;15.95,-42.12,;17.28,-39.8,;18.61,-40.57,;18.61,-42.11,;19.94,-42.88,;17.27,-42.88,;19.94,-39.8,;19.94,-38.26,;21.27,-40.57,;22.61,-39.8,;22.61,-38.26,;21.27,-37.49,;23.93,-37.49,;23.94,-40.57,;23.94,-42.11,;25.27,-39.8,;26.6,-40.57,;26.6,-42.11,;27.93,-42.88,;27.93,-44.42,;29.26,-45.18,;29.26,-46.72,;27.93,-47.49,;30.6,-47.49,;27.93,-39.8,;27.93,-38.26,;29.26,-40.56,;30.6,-39.8,;30.6,-38.26,;31.93,-37.49,;31.93,-35.95,;30.6,-35.18,;33.27,-35.18,;31.93,-40.57,;31.93,-42.11,;33.26,-39.8,;34.59,-40.57,;34.59,-42.11,;35.92,-42.88,;35.92,-44.42,;37.26,-45.18,;37.26,-46.72,;35.92,-47.49,;38.59,-47.49,;35.92,-39.8,;35.92,-38.26,;37.26,-40.57,;38.59,-39.8,;38.59,-38.26,;39.92,-37.49,;41.26,-38.26,;42.6,-37.49,;42.6,-35.95,;43.92,-35.18,;41.26,-35.18,;39.92,-35.95,;39.92,-40.57,;41.26,-39.8,;39.92,-42.11,)|
Structure
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