| Reaction Details |
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 | Report a problem with these data |
| Target | D(3) dopamine receptor |
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| Ligand | BDBM55121 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_2280437 |
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| EC50 | 6.1±n/a nM |
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| Citation |  Dinda, B; Das, B; Biswas, S; Sharma, H; Armstrong, C; Yedlapudi, D; Antonio, T; Reith, M; Dutta, AK Bivalent dopamine agonists with co-operative binding and functional activities at dopamine D2 receptors, modulate aggregation and toxicity of alpha synuclein protein. Bioorg Med Chem78:0 (2023) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| D(3) dopamine receptor |
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| Name: | D(3) dopamine receptor |
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| Synonyms: | DRD3 | DRD3_HUMAN | Dopamine D3 receptor |
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| Type: | PROTEIN |
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| Mol. Mass.: | 44213.40 |
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| Organism: | Homo sapiens |
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| Description: | ChEMBL_105671 |
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| Residue: | 400 |
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| Sequence: | MASLSQLSGHLNYTCGAENSTGASQARPHAYYALSYCALILAIVFGNGLVCMAVLKERAL
QTTTNYLVVSLAVADLLVATLVMPWVVYLEVTGGVWNFSRICCDVFVTLDVMMCTASILN
LCAISIDRYTAVVMPVHYQHGTGQSSCRRVALMITAVWVLAFAVSCPLLFGFNTTGDPTV
CSISNPDFVIYSSVVSFYLPFGVTVLVYARIYVVLKQRRRKRILTRQNSQCNSVRPGFPQ
QTLSPDPAHLELKRYYSICQDTALGGPGFQERGGELKREEKTRNSLSPTIAPKLSLEVRK
LSNGRLSTSLKLGPLQPRGVPLREKKATQMVAIVLGAFIVCWLPFFLTHVLNTHCQTCHV
SPELYSATTWLGYVNSALNPVIYTTFNIEFRKAFLKILSC
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| BDBM55121 |
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| n/a |
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| Name | BDBM55121 |
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| Synonyms: | 3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)benzene-1,2-diol;hydrochloride | 4-(2-aminoethyl)pyrocatechol;hydrochloride | 4-(2-azanylethyl)benzene-1,2-diol;hydrochloride | Dopamine | MLS000069419 | SMR000059081 | cid_65340 |
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| Type | Small organic molecule |
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| Emp. Form. | C8H11NO2 |
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| Mol. Mass. | 153.1784 |
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| SMILES | NCCc1ccc(O)c(O)c1 |
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| Structure | 
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