| Reaction Details |
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 | Report a problem with these data |
| Target | Purine nucleoside phosphorylase |
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| Ligand | BDBM50610707 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_2281753 |
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| IC50 | 40000±n/a nM |
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| Citation |  Alizadeh, SR; Ebrahimzadeh, MA Pyrazolotriazines: Biological activities, synthetic strategies and recent developments. Eur J Med Chem223:0 (2021) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Purine nucleoside phosphorylase |
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| Name: | Purine nucleoside phosphorylase |
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| Synonyms: | Inosine phosphorylase | Inosine-guanosine phosphorylase | NP | PNP | PNPH_HUMAN | Purine nucleoside phosphorylase (PNPase) |
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| Type: | Enzyme |
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| Mol. Mass.: | 32119.53 |
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| Organism: | Homo sapiens (Human) |
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| Description: | n/a |
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| Residue: | 289 |
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| Sequence: | MENGYTYEDYKNTAEWLLSHTKHRPQVAIICGSGLGGLTDKLTQAQIFDYGEIPNFPRST
VPGHAGRLVFGFLNGRACVMMQGRFHMYEGYPLWKVTFPVRVFHLLGVDTLVVTNAAGGL
NPKFEVGDIMLIRDHINLPGFSGQNPLRGPNDERFGDRFPAMSDAYDRTMRQRALSTWKQ
MGEQRELQEGTYVMVAGPSFETVAECRVLQKLGADAVGMSTVPEVIVARHCGLRVFGFSL
ITNKVIMDYESLEKANHEEVLAAGKQAAQKLEQFVSILMASIPLPDKAS
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| BDBM50610707 |
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| n/a |
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| Name | BDBM50610707 |
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| Synonyms: | CHEMBL5279874 |
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| Type | Small organic molecule |
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| Emp. Form. | C6H9N5S |
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| Mol. Mass. | 183.234 |
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| SMILES | CSC1=NNC2NN=C(C)C2=N1 |c:11,t:2,7| |
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| Structure | 
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