| Reaction Details |
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 | Report a problem with these data |
| Target | GTPase KRas |
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| Ligand | BDBM50610920 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_2282397 |
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| IC50 | 50000±n/a nM |
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| Citation |  Fan, G; Lou, L; Song, Z; Zhang, X; Xiong, XF Targeting mutated GTPase KRAS in tumor therapies. Eur J Med Chem226:0 (2021) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| GTPase KRas |
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| Name: | GTPase KRas |
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| Synonyms: | GTPase KRas, N-terminally processed | K-Ras 2 | KRAS | KRAS2 | Ki-Ras | RASK2 | RASK_HUMAN | c-K-ras | c-Ki-ras |
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| Type: | PROTEIN |
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| Mol. Mass.: | 21656.10 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_1476955 |
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| Residue: | 189 |
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| Sequence: | MTEYKLVVVGAGGVGKSALTIQLIQNHFVDEYDPTIEDSYRKQVVIDGETCLLDILDTAG
QEEYSAMRDQYMRTGEGFLCVFAINNTKSFEDIHHYREQIKRVKDSEDVPMVLVGNKCDL
PSRTVDTKQAQDLARSYGIPFIETSAKTRQRVEDAFYTLVREIRQYRLKKISKEEKTPGC
VKIKKCIIM
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|
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| BDBM50610920 |
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| n/a |
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| Name | BDBM50610920 |
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| Synonyms: | CHEMBL5269554 |
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| Type | Small organic molecule |
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| Emp. Form. | C18H22Cl2N4O3 |
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| Mol. Mass. | 413.298 |
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| SMILES | Oc1cc(Cl)c(Cl)cc1NCC(=O)N1CCN(CC1)C1CN(C1)C(=O)C=C |
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| Structure | 
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